Utility of the PHQ-9 to identify major depressive disorder in adult patients in Spanish primary care centres

BMC Psychiatry

Table 3 PHQ-9 operational characteristics

Cut-off Score	Sensitivity	Specificity	Positive Predictive Value	Negative Predictive Value	Positive Likelihood Ratio	Negative Likelihood Ratio	Youden’s Index (J)
PHQ-9 ≥ 8	.98 (.94–.99)	.51 (.37–.64)	.84	.89	1.99 (1.50–2.66)	.05 (.01–.14)	.49
PHQ-9 ≥ 9	.96 (.91–.98)	.59 (.45–.72)	.86	.85	2.36 (1.68–3.30)	.07 (.03–.16)	.55
PHQ-9 ≥ 10	.95 (.89–.97)	.67 (.53–.79)	.88	.83	2.90 (1.93–4.34)	.08 (.04–.17)	.62
PHQ-9 ≥ 11	.90 (.84–.94)	.73 (.60–.84)	.90	.73	3.39 (2.11–5.42)	.14 (.08–.24)	.63
PHQ-9 ≥ 12	.84 (.77–.90)	.78 (.64–.87)	.91	.66	3.76 (2.22–6.37)	.20 (.13–.31)	.62
PHQ-9 ≥ 13	.80 (.72–.86)	.84 (.71–.91)	.93	.61	4.89 (2.58–9.27)	.24 (.17–.35)	.64
PHQ-9 ≥ 14	.78 (.70–.84)	.88 (.76–.94)	.94	.60	6.33 (2.98–13.47)	.26 (.18–.36)	.66
Algorithm^a	.88 (.82–.93)	.80 (.66–.88)	.92	.72	4.33 (2.48–7.55)	.15 (.09–.24)	.68

^aMDD is diagnosed if at least one of the first symptoms (items) is rated with a 2 (more than half of the days) or a 3 (most days)

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