Association of schizophrenia onset age and white matter integrity with treatment effect of D-cycloserine: a randomized placebo-controlled double-blind crossover study

Table 4 Differences of DCS-effect by onset age

		DCS-effect	SD	F value	p value
PANSS				2.20	0.11
Positive	EOS	0.83	1.83	1.54	0.22
	non-EOS	−0.07	1.39
Negative	EOS	2.17	2.79	6.17	0.02
	non-EOS	−0.07	1.76
General	EOS	1.33	3.50	1.72	0.20
	non-EOS	−0.60	3.07
SANS				1.11	0.38
I	EOS	1.50	2.74	2.02	0.16
	non-EOS	−0.40	2.49
II	EOS	0.50	0.84	0.57	0.46
	non-EOS	−0.23	1.72
III	EOS	−0.50	1.52	0.20	0.66
	non-EOS	−0.10	1.60
IV	EOS	0.17	1.33	0.54	0.47
	non-EOS	−0.50	1.81
V	EOS	0.67	1.51	0.70	0.41
	non-EOS	−0.23	1.76
Summary	EOS	0.83	1.83	1.95	0.17
	non-EOS	−0.30	1.51
Total	EOS	2.33	5.82	0.92	0.34
	non-EOS	−1.47	7.22
BACS				0.85	0.56
VM	EOS	−2.83	9.28	1.64	0.21
	non-EOS	0.68	5.12
DS	EOS	−0.17	2.32	0.19	0.66
	non-EOS	−0.68	3.42
TM	EOS	0.67	5.75	0.47	0.50
	non-EOS	−3.96	14.86
SC	EOS	−1.67	6.12	0.01	0.94
	non-EOS	−1.39	7.02
VFC	EOS	−3.17	3.54	2.69	0.11
	non-EOS	0.04	3.70
VFL	EOS	0.67	3.14	0.51	0.48
	non-EOS	−0.61	5.79
TOL	EOS	0.00	3.69	0.02	0.90
	non-EOS	−0.29	3.75
EQS				1.18	0.34
intra	EOS	−0.60	12.82	0.86	0.36
	non-EOS	2.58	6.10
inter	EOS	−2.40	9.21	0.65	0.43
	non-EOS	0.17	8.69
situa	EOS	3.00	6.12	0.53	0.47
	non-EOS	0.79	6.06

PANSS Positive and Negative Syndrome Scale, SANS Scale for the Assessment of Negative Symptoms, BACS Brief Assessment of Cognition in Schizophrenia, VM verbal memory, DS digit sequencing task, TM token motor task, SC symbolic coding, VFC verbal fluency of category, VFL verbal fluency of letter, TOL tower of London, EQS Emotional Intelligence Scale, intra intrapersonal domain, inter interpersonal domain, situa situational domain, SD standard deviation; DCS-effect, scores at DCS phase extracted by those at PCB phase

ISSN: 1471-244X