Risk factors for dementia in the ninth decade of life and beyond: a study of the Lothian birth cohort 1921

BMC Psychiatry

Table 4 Logistic regression results

	Odds ratios (95% CI) for probable dementia
	Model 1 (n = 234)	Model 2 (n = 377)
APOE ɛ4	2.15 (1.04,4.42)	2.37 (1.37,4.07)
Height (z score)	0.71 (0.49, 1.01)	0.73 (0.56, 0.96)
Hypertension	0.47 (0.23,0.98)	0.55 (0.32,0.93)
Current smoking	0.18 (0.02, 1.41)	0.25 (0.06, 1.09)
Lifetime physical activity	1.14 (1.02,1.28)	-

The variables entered into the analyses for each model were as follows: Model 1- age, sex, APOE ɛ4 carrier status, age 11 IQ (z score), number of teeth, height (z score), years in education, history of diabetes, HbA1c, history of hypertension, systolic blood pressure, diastolic blood pressure, cholesterol, use of statins, HADS depression score, BMI, smoking status, physical activity in occupation, lifetime physical activity (‘backward conditional’ method); Model 2- as model 1, but physical activity in occupation and lifetime physical activity excluded (‘backward conditional’ method)

ISSN: 1471-244X