Deficits of perceived spatial separation induced prepulse inhibition in patients with schizophrenia: relationships to symptoms and neurocognition

Table 7 Results of stepwise multiple regression analysis

PPI task	Predictor	Beta	S.E.	t	p
HC (n = 50)
PSC-PPI	Gender	26.00	7.41	3.51	0.00
Adjusted R² = 0.28;	ATT	0.56	0.20	2.79	0.01
F _(4,45) = 5.88; p < 0.001
PSS-PPI	Gender	33.81	7.83	4.31	0.00
Adjusted R² = 0.37;	Cigarettes per day	−0.95	0.43	−2.22	0.03
F _(6,43) = 5.88; p < 0.001	ATT	0.61	0.19	3.23	0.00
F _(6,43) = 5.88; p < 0.001	INT-W	-0.77	0.32	−2.38	0.02
SZ (n = 75)
PSC-PPI	ATT	1.17	0.43	2.27	0.01
Adjusted R² = 0.09;	TOT	2.04	0.82	2.49	0.02
F _(8,66) = 1.96; p > 0.05
PSS-PPI	Education	3.05	1.27	2.41	0.02
Adjusted R² = 0.17;	Recurrence times	−3.10	1.25	−2.48	0.00
F _(8,66) = 2.85; p < 0.05	ATT	1.18	0.32	3.70	0.00
F _(8,66) = 2.85; p < 0.05	TOT	1.86	0.48	3.86	0.00

Note: S.E standard error, SZ Schizophrenia patients, HC healthy controls. PPI prepulse inhibition, PSC-PPI perceived spatial co-location PPI, PSS-PPI perceived spatial separation PPI. ATT attention score, TOT total composite score, INT-W word interference time

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