Deficits of perceived spatial separation induced prepulse inhibition in patients with schizophrenia: relationships to symptoms and neurocognition

Table 3 Logistic regression model for different PPI distinguishing schizophrenia patients from healthy controls (ISI = 120 ms)

Predictor	χ²	df	p	OR	95% CI	R ²	Sensitivity	Specificity	Accuracy	PPV	NPV	AUC
PSC-PPI	14.6	1	0.00	0.97	0.95-0.98	0.17	75.0	52.0	72.0	72.7	70.3	72.0
PSS-PPI	29.3	1	0.00	0.94	0.93-0.96	0.46	87.0	66.0	78.4	79.3	76.7	85.2*

Note: The goodness-of-fit (χ²) and effect size indicator (Nagelkerke’s R²) measure how well the model represents the diagnostic groupings. ISI inter-stimulus interval, PPI prepulse inhibition, PSC-PPI perceived spatial co-location PPI, PSS-PPI perceived spatial separation PPI, PPV positive predictive value, NPV negative predictive value, AUC area under ROC curve; * indicates p < 0.05 for DeLong’s test

ISSN: 1471-244X