Table 4 Comparison of pharmacotherapy among depressed eating disorder patients with or without lifetime hypomania/mania episode at enrollment
Variables | Eating disorders with MDD | Eating disorders with bipolar II disorder | Eating disorders with bipolar I disorder | 2 vs. 1 | 3 vs. 1 | 3 vs. 2 |
|---|---|---|---|---|---|---|
(1) | (2) | (3) | ||||
(n = 133) | (n = 55) | (n = 39) | ||||
N (%) | N (%) | N (%) | AOR (95% CI) | AOR (95% CI) | AOR (95% CI) | |
Antidepressant monotherapy | 61 (48.0) | 31 (56.4) | 10 (27.0) | 1.23 (0.62, 2.42) | 0.35 (0.15, 0.83) | 0.28 (0.11, 0.72) |
mood stabilizer monotherapy | 0 | 1 (1.8) | 0 | NA | NA | NA |
Atypical antipsychotic monotherapy | 32 (25.2) | 6 (10.9) | 9 (24.3) | 0.41 (0.15, 1.09) | 1.04 (0.41, 2.61) | 2.65 (0.82, 8.59) |
Antidepressant plus mood stabilizers | 1 (0.8) | 0 | 1 (2.7) | NA | NA | NA |
Antidepressant plus antipsychotic | 17 (13.4) | 10 (18.2) | 9 (24.3) | 1.44 (0.56, 3.47) | 2.09 (0.81, 5.37) | 1.36 (0.46, 4.03) |
Antidepressant plus mood stabilizers and antipsychotics | 1 (0.8) | 1 (1.8) | 1 (2.7) | 2.26 (0.13, 39.12) | 4.00 (0.23, 68.78) | 1.78 (0.10, 30.80) |
Any antidepressant | 80 (63.0) | 42 (76.4) | 21 (56.8) | 1.70 (0.78, 3.72) | 0.70 (0.31, 1.60) | 0.38 (0.15, 0.99) |
Any mood stabilizer | 5 (3.9) | 3 (5.5) | 6 (16.2) | 1.01 (0.25, 4.88) | 3.95 (1.06, 14.71) | 3.96 (0.90, 17.44) |
Any atypical antipsychotic | 51 (40.2) | 17 (30.9) | 21 (56.8) | 0.72 (0.36, 1.47) | 2.13 (0.97, 4.65) | 2.92 (1.18, 7.20) |