From: Association between CHADS2 score, depressive symptoms, and quality of life in a general population
Variable | All (n = 11,060) | Depressive symptoms | P value | |
---|---|---|---|---|
No or mild (n = 10,390) | Moderate or severe (n = 670) | |||
Age, years | 53.9 ± 10.5 | 53.7 ± 10.5 | 57.1 ± 10.2 | <0.001 |
Male | 5080 (45.9) | 4898 (47.1) | 182 (27.2) | <0.001 |
BMI, kg/m2 | 24.8 ± 3.7 | 24.8 ± 3.7 | 24.5 ± 3.8 | 0.050 |
SBP, mmHg | 141.6 ± 23.3 | 141.5 ± 23.2 | 143.5 ± 25.5 | 0.051 |
DBP, mmHg | 82.0 ± 11.7 | 82.0 ± 11.7 | 82.2 ± 11.8 | 0.603 |
FBG, mmol/L | 5.91 ± 1.62 | 5.90 ± 1.61 | 6.09 ± 1.76 | 0.006 |
TC, mmol/L | 5.24 ± 1.09 | 5.23 ± 1.08 | 5.31 ± 1.18 | 0.124 |
TG, mmol/L | 1.63 ± 1.47 | 1.62 ± 1.47 | 1.75 ± 1.51 | 0.030 |
HDL-C, mmol/L | 1.41 ± 0.38 | 1.41 ± 0.38 | 1.40 ± 0.40 | 0.601 |
LDL-C, mmol/L | 2.93 ± 0.82 | 2.92 ± 0.82 | 2.96 ± 0.89 | 0.290 |
Serum uric acid, umol/L | 292 ± 85 | 292 ± 85 | 289 ± 90 | 0.344 |
eGFR, ml/min/1.73 m2 | 92.8 ± 15.9 | 93.1 ± 15.7 | 88.6 ± 18.3 | <0.001 |
Current smoker | 3886 (35.1) | 3693 (35.5) | 193 (28.8) | <0.001 |
Current drinker | 2474 (22.4) | 2402 (23.1) | 72 (10.7) | <0.001 |
Education level | <0.001 | |||
≤ Primary school | 5539 (50.1) | 5095 (49.0) | 444 (66.3) | |
Middle school | 4491 (40.6) | 4296 (41.3) | 195 (29.1) | |
≥ High school | 1030 (9.3) | 999 (9.6) | 31 (4.6) | |
Family income, CNY/year | <0.001 | |||
≤ 5000 | 1379 (12.5) | 1209 (11.6) | 170 (25.4) | |
5000–20,000 | 6025 (54.5) | 5655 (54.4) | 370 (55.2) | |
> 20,000 | 3656 (33.1) | 3526 (33.9) | 130 (19.4) | |
Physical activity | <0.001 | |||
Low | 3263 (29.5) | 2953 (28.4) | 310 (46.3) | |
Moderate | 7164 (64.8) | 6830 (65.7) | 334 (49.9) | |
High | 633 (5.7) | 607 (5.8) | 26 (3.9) | |
Sleep duration, h/day | 7.3 ± 1.7 | 7.3 ± 1.6 | 6.2 ± 2.1 | <0.001 |
Congestive heart failure | 102 (0.9) | 78 (0.8) | 24 (3.6) | <0.001 |
Hypertension | 5623 (50.8) | 5234 (50.4) | 389 (58.1) | <0.001 |
Age ≥ 75 years | 332 (3.0) | 297 (2.9) | 35 (5.2) | 0.001 |
Diabetes mellitus | 1154 (10.4) | 1051 (10.1) | 103 (15.4) | <0.001 |
Stroke | 976 (8.8) | 848 (8.2) | 128 (19.1) | <0.001 |
CHADS2 score | 0.83 ± 0.96 | 0.80 ± 0.94 | 1.20 ± 1.25 | <0.001 |
WHOQOL-BREF domain | ||||
Physical health | 15.1 ± 2.3 | 15.4 ± 2.1 | 11.5 ± 2.5 | <0.001 |
Psychological | 14.5 ± 2.4 | 14.8 ± 2.2 | 10.7 ± 2.6 | <0.001 |
Social relationships | 14.6 ± 2.1 | 14.7 ± 2.0 | 13.0 ± 2.4 | <0.001 |
Environment | 13.5 ± 2.1 | 13.6 ± 2.1 | 11.7 ± 2.1 | <0.001 |