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Table 4 Atypical antipsychotic AEs reported by physicians as clinically important and/or bothersome

From: Assessing the burden of treatment-emergent adverse events associated with atypical antipsychotic medications

AEs, n (%)

Clinically important

(n = 4)

Most clinically important

(n = 4)

Most bothersome to patients

(n = 4)

Metabolic syndrome a

4 (100)

4 (100)

n/a

Weight gain

4 (100)

2 (50)

4 (100)

Reduced sexual desire or performance

4 (100)

1 (25)

2 (50)

Neutropenia b

3 (75)

3 (75)

1 (25)

Hyperglycemia b

3 (75)

2 (50)

0

EPS b

3 (75)

1 (25)

2 (50)

Hyperlipidemia

3 (75)

1 (25)

0

Akathisia

3 (75)

0

2 (50)

QT prolongation b

2 (50)

2 (50)

0

Major medical (seizures)

2 (50)

1 (25)

1 (25)

Hormonal

2 (50)

0

2 (50)

Hypotension

2 (50)

0

1 (25)

Cognitive issues

2 (50)

0

1 (25)

Major medical (diabetes) b

1 (25)

1 (25)

1 (25)

Hypertension

1 (25)

1 (25)

0

Low energy

1 (25)

0

1 (25)

Depressive symptoms

1 (25)

0

0

Flat/restricted affect

1 (25)

0

0

Somnolence/sedation

1 (25)

0

0

  1. Abbreviations: AE adverse event, EPS extrapyramidal symptoms, QT time between the start of the Q wave and the end of the T wave in the heart’s electrical cycle
  2. a Reported as “most clinically important” in the group setting but not the individual task
  3. b Reported as “most clinically important” in the group setting and in the individual task