From: Changes in event-related potentials in patients with first-episode schizophrenia and their siblings
Emotion | Intensity | Site | Healthy controls | Schizophrenia | Sibling risk group | F | P |
---|---|---|---|---|---|---|---|
P100 Amplitude | |||||||
Disgust | Low | O2 | 4.41 ± 2.93 | 3.25 ± 2.95 | 9.30 ± 2.40*# | 20.498 | <0.001 |
P7 | 3.22 ± 2.54 | 2.86 ± 1.48 | 6.33 ± 2.46*# | 12.903 | <0.001 | ||
Moderate | O2 | 4.76 ± 2.91 | 3.21 ± 3.68 | 10.56 ± 2.76*# | 22.833 | <0.001 | |
P7 | 3.20 ± 1.92 | 2.68 ± 1.85 | 6.39 ± 2.65*# | 14.763 | <0.001 | ||
P8 | 5.33 ± 2.32 | 3.88 ± 2.95* | 7.45 ± 3.33*# | 6.882 | 0.002 | ||
High | O2 | 4.58 ± 2.80 | 3.84 ± 3.42 | 9.94 ± 2.35*# | 18.900 | <0.001 | |
P7 | 3.21 ± 2.49 | 2.93 ± 1.73 | 6.22 ± 2.99*# | 9.772 | <0.001 | ||
P8 | 5.77 ± 2.47 | 4.30 ± 3.16* | 7.96 ± 3.21*# | 6.698 | 0.002 | ||
Happiness | Low | O2 | 4.16 ± 2.78 | 3.73 ± 2.89 | 8.72 ± 2.10*# | 15.030 | <0.001 |
P7 | 2.97 ± 2.50 | 3.08 ± 1.79 | 5.60 ± 2.74*# | 6.106 | 0.004 | ||
Moderate | O2 | 4.26 ± 3.13 | 3.59 ± 2.65 | 8.69 ± 2.85*# | 14.624 | <0.001 | |
P7 | 3.37 ± 2.53 | 2.75 ± 1.87 | 5.97 ± 2.54*# | 9.143 | <0.001 | ||
P8 | 5.26 ± 2.79 | 4.36 ± 2.77 | 6.96 ± 3.26# | 3.502 | 0.037 | ||
High | O2 | 4.57 ± 2.88 | 4.51 ± 2.79 | 10.54 ± 2.23*# | 24.627 | <0.001 | |
P7 | 3.85 ± 2.57 | 3.04 ± 1.52 | 7.11 ± 1.86*# | 18.537 | <0.001 | ||
Fear | Low | O2 | 4.25 ± 2.37 | 4.00 ± 2.28 | 9.68 ± 2.08*# | 30.456 | <0.001 |
P7 | 2.70 ± 2.51 | 2.98 ± 1.80 | 6.95 ± 2.08*# | 18.939 | <0.001 | ||
P8 | 4.56 ± 2.64 | 4.13 ± 2.45 | 7.02 ± 2.89*# | 5.559 | 0.006 | ||
Moderate | O1 | 3.88 ± 3.05 | 3.54 ± 2.16 | 5.93 ± 1.84*# | 4.427 | 0.017 | |
O2 | 4.29 ± 2.52 | 3.75 ± 2.69 | 8.27 ± 1.77*# | 15.671 | <0.001 | ||
P7 | 2.99 ± 2.53 | 2.54 ± 1.31 | 5.37 ± 2.61*# | 8.352 | 0.001 | ||
High | O2 | 4.70 ± 2.53 | 4.25 ± 2.57 | 10.09 ± 2.12*# | 26.673 | <0.001 | |
P7 | 3.54 ± 2.38 | 3.11 ± 1.57 | 6.47 ± 2.19*# | 12.968 | <0.001 | ||
P100 latency | |||||||
Disgust | Moderate | O1 | 119.50 ± 16.85 | 119.26 ± 22.60 | 90.85 ± 23.76*# | 9.061 | <0.001 |
O2 | 120.11 ± 19.25 | 102.63 ± 29.21* | 115.46 ± 16.50 | 3.156 | 0.050 | ||
High | O1 | 116.00 ± 17.22 | 115.04 ± 23.17 | 80.31 ± 30.78*# | 11.269 | <0.001 | |
Happiness | High | O1 | 118.44 ± 19.64 | 119.08 ± 22.17 | 99.92 ± 23.21*# | 3.808 | 0.028 |
Fear | Moderate | O1 | 111.83 ± 24.34 | 122.31 ± 20.56 | 103.92 ± 22.42# | 3.201 | 0.049 |
High | O1 | 121.89 ± 19.12 | 114.92 ± 28.07 | 92.08 ± 26.18*# | 5.650 | 0.006 | |
N170 Amplitude | |||||||
Happy | Low | O2 | 2.17 ± 2.56 | 1.92 ± 2.74 | 4.73 ± 3.58*# | 4.216 | 0.020 |
N170 latency | |||||||
Disgust | Low | P8 | 171.95 ± 15.96 | 185.11 ± 16.45* | 170.54 ± 14.04# | 5.958 | 0.005 |
Moderate | P8 | 173.39 ± 11.58 | 185.37 ± 16.38* | 171.69 ± 11.54# | 5.947 | 0.005 | |
High | P8 | 176.50 ± 10.93 | 184.26 ± 13.14* | 172.23 ± 10.56# | 5.088 | 0.009 | |
Happiness | Moderate | O1 | 178.89 ± 15.95 | 184.54 ± 20.53 | 196.46 ± 17.94* | 3.422 | 0.040 |
P8 | 175.00 ± 11.55 | 186.69 ± 16.85* | 172.85 ± 12.23# | 5.513 | 0.007 | ||
High | P7 | 177.28 ± 16.62 | 179.72 ± 24.47 | 159.46 ± 23.19*# | 3.899 | 0.026 | |
P8 | 173.44 ± 15.86 | 185.56 ± 18.27* | 174.46 ± 11.94 | 3.596 | 0.034 | ||
Fear | Moderate | O1 | 179.61 ± 14.46 | 174.27 ± 25.56 | 199.00 ± 20.92*# | 5.804 | 0.005 |
P8 | 174.72 ± 12.43 | 182.27 ± 14.42* | 170.62 ± 11.46# | 3.855 | 0.027 | ||
High | O2 | 173.17 ± 17.05 | 189.73 ± 20.45* | 170.62 ± 13.26# | 6.855 | 0.002 | |
P8 | 175.28 ± 13.06 | 186.92 ± 15.08* | 171.38 ± 12.93# | 6.649 | 0.003 | ||
N250 Amplitude | |||||||
Fear | High | F3 | 2.18 ± 1.65 | 2.26 ± 1.21 | 3.87 ± 1.71*# | 6.307 | 0.003 |
N250 latency | |||||||
Happiness | Low | F3 | 271.62 ± 59.72 | 253.35 ± 53.38 | 318.92 ± 29.66*# | 5.481 | 0.007 |
Moderate | F3 | 268.05 ± 56.72 | 261.13 ± 58.93 | 315.00 ± 40.72*# | 4.308 | 0.018 | |
F4 | 257.29 ± 43.70 | 262.70 ± 47.27 | 308.85 ± 38.41*# | 7.115 | 0.002 | ||
High | F4 | 252.71 ± 49.28 | 254.95 ± 55.33 | 314.15 ± 24.42*# | 8.153 | 0.001 | |
Disgust | Low | F3 | 280.57 ± 47.55 | 286.52 ± 43.02 | 319.46 ± 28.48*# | 3.915 | 0.026 |
Moderate | F3 | 278.27 ± 43.37 | 266.04 ± 51.72 | 313.15 ± 40.15*# | 3.981 | 0.024 | |
High | F4 | 251.59 ± 49.60 | 256.22 ± 56.27 | 304.77 ± 42.57*# | 4.999 | 0.010 | |
Fear | Low | F4 | 277.00 ± 42.43 | 250.78 ± 53.06 | 301.54 ± 35.87# | 3.920 | 0.026 |
FC3 | 274.14 ± 47.56 | 253.09 ± 53.71 | 312.23 ± 43.91*# | 4.746 | 0.013 | ||
Moderate | F3 | 265.10 ± 45.55 | 279.30 ± 49.57 | 313.38 ± 38.47*# | 4.585 | 0.014 | |
High | F3 | 274.67 ± 50.85 | 269.70 ± 56.07 | 313.92 ± 41.08*# | 3.627 | 0.033 | |
FC3 | 271.90 ± 52.56 | 263.41 ± 61.82 | 316.85 ± 32.06*# | 4.774 | 0.012 |