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Table 1 Summary table of general characteristics and results from studies included in a systematic literature review on psychiatric readmissions and their association with physical comorbidity

From: Psychiatric readmissions and their association with physical comorbidity: a systematic literature review

 

N of studies

Comments

Publication date

1991 - 1999: 6

2000–2009: 11

2010–2013: 6

4 studies: 2011

2 studies/year: 2009, 2006, 2000,1997

1 study in all other years

Country

USA: 14

Canada: 2

Denmark: 2

Australia: 2

UK: 1

Spain: 1

Japan: 1

61% of included studies were carried out in USA

Source of data

Hospital medical records only: 10

Big administrative database (National registries): 7

Hospital medical records + Interviews and/or Self- assessment questionnaires, Clinical assessment instruments: 6

44% of included studies used data from hospital medical records

Applied statistical method /model

Only descriptive statistics / nonparametric test: 4

Bivariate / Multivariate statistical analysis: 19

83% of included studies applied Bivariate / Multivariate statistical analyses

Study population according to age

Age range: 18 – 80+

Studies focusing on elderly population: 5

22% of included studies focused on elderly population

Study population according to gender

Both: 21

Only female: 1

Only man: 1

In 2 studies with veterans were included males or females only, recruited from Veterans hospital

Categories of psychiatric diagnoses included in the study (as index disease)

Affective disorders: 7

Substances use disorders: 7

All psychiatric diagnoses: 6

Serious mental illness: 3

30,5% of studies recruited patients with affective and substances use disorders; 26% with all psychiatric diagnoses; 13% with serious mental illness

Affective disorders include: depression, bipolar disorder

Serious mental illness include: schizophrenia, schizoaffective disorder, bipolar disorder, personality disorders

Types of physical comorbidity variables included in studies

Specified physical comorbidity (with ICD codes): 6

Specified physical comorbidity (without ICD codes): 6

Charlson Comorbidity Index : 5

Not specified physical comorbidity: 5

Number of medical diagnoses and somatic complaints: 3

In 2 studies were applied two types of physical comorbidity variables within the same study protocol: Charlson Comorbidity Index + Specified physical comorbidity (with ICD codes) / Specified physical comorbidity (without ICD codes)

Most common physical comorbidity variables documented at admission/discharge in the category ”Affective disorders ”

Medical diagnoses/illness: Medical illness (not specified), Diabetes, Hyperthyroidism, Obesity, Cardiovascular disease, Hypertension, High cholesterol

Variables describing the burden of medical illness: Somatic complaints (excessive concern with body or functional capacity), The number of medical diagnoses, Charlson Comorbidity Index

 

Most common physical comorbidity variables documented at admission/discharge in the category “Substances use disorders ”

Medical diagnoses/illness: Chronic lung conditions, Asthma, Hepatitis C virus (HCV) infection, Hepatitis B,HIV(+), Epilepsy, Hypothyroidism, Hypertension, Skin and subcutaneous tissue diseases, Infectious parasitic diseases, Digestive diseases, Cardiac problems/angina, Cirrhosis, Gastritis, Diabetes, Pregnancy, Accidental poisonings, Adverse drug reactions, Accidental falls

Variables describing the burden of medical illness: Physical health problems, Charlson Comorbidity Index, Number of medical diagnosis

 

Most common physical comorbid variables documented at admission/discharge in the category

“All psychiatric diagnoses ”

Medical diagnoses/illness: Cellulitis, Chronic obstructive pulmonary disease, Liver disease, Diabetes, Hypertension, Circulatory heart conditions, Epilepsy, Hypothyroidism

Variables describing the burden of medical illness: Charlson Comorbidity Index, Number of medical diagnoses

 

Most common physical comorbidity variables documented at admission/discharge in the category “Serious mental illness ”

Variables describing the burden of medical illness: Non specified physical health problems, Charlson Comorbidity Index

None of reviewed studies in the category “Serious mental illness“did document medical diagnoses/illness

Data on mortality

NO: 19

YES: 4

83% studies did not analyse mortality

Readmission time

12 months: 5

1 month: 3

6 months: 2

3 months: 2

24 months: 2

26 months: 2

48 months: 2

Other less frequently used time frames for readmission time: less than 1 month (8–30 days), 58 months, 70 months, 79 months, 84 months, 192 months, 216 months, 240 months

The impact of physical comorbidity variables on readmission

YES: 12

NO: 4

NA: 7

52% of included studies did show that physical comorbidity may be associated with hospital readmission

6 studies documented physical comorbidity only at admission/discharge without including them at readmission

Most common physical comorbidity variables with higher probability for readmission according to categories of psychiatric diagnoses

Affective disorders: Not specified medical illness, Somatic complaints, Number of medical diagnoses, Hyperthyroidism

Substances use disorders: Chronic lung conditions, Hepatitis C virus (HCV) infection, Hypertension, Number of medical diagnoses

All psychiatric diagnoses: Cellulitis, Chronic obstructive pulmonary disease, Liver disease, Diabetes, Hypertension, Circulatory heart conditions

Serious mental illness: Higher Charlson Comorbidity Index, Somatic complaints, Physical health problems

 

Applied concept of comorbidity construct

Multimorbidity: 11

Patient’s complexity: 7

Morbidity burden: 4

Comorbidity: 1

Applied concept of comorbidity construct according to categories of psychiatric diagnoses:

Affective disorders: Morbidity burden N = 3; Multimorbidity N = 2; Patient’s complexity N = 1; Comorbidity N = 1

Substances use disorders: Multimorbidity N = 6; Patient’s complexity N = 1

All psychiatric diagnoses: Patient’s complexity N = 4; Multimorbidity N = 2

Serious mental illness: Multimorbidity N = 1; Patient’s complexity N = 1; Morbidity burden N = 1

  1. aComorbidity: presence of additional diseases in relation to an index disease in one individual
  2. Multimorbidity: presence of multiple diseases in one individual
  3. Morbidity burden: overall impact of the different diseases in an individual taking into account their severity
  4. Patient’s complexity: overall impact of the different diseases in an individual taking into account their severity and other health-related attributes