Smoking in pregnancy, adolescent mental health and cognitive performance in young adult offspring: results from a matched sample within a Finnish cohort

Table 4 Effect of potential mediating factors on the relationship between prenatal exposure to maternal cigarette smoking (PEMCS) and vocabulary and matrix reasoning in males (n = 132)

Model	Vocabulary		Matrix reasoning
	Coefficient (95% confidence interval)	P-value	Coefficient (95% confidence interval)	P-value
Model 1^a	-0.444 (-0.783, -0.104)	0.011	-0.379 (-0.711, -0.047)	0.026
Model 2^b	-0.456 (-0.789, -0.122)	0.008	-0.380 (-0.715, -0.046)	0.026
Model 2 + PLEs	-0.460 (-0.794, -0.123)	0.007	-0.383 (-0.719, -0.048)	0.025
Model 2 + inattention and hyperactivity Z-score	-0.382 (-0.730, -0.034)	0.032	-0.300 (-0.648, 0.048)	0.091
Model 1 + other externalizing behavior Z-score	-0.527 (-0.862, -0.192)	0.002	-0.395 (-0.737, -0.053)	0.024

^a Model 1 coefficient is association between PEMCS and vocabulary or matrix reasoning in males
^b Model 2 coefficient is association between PEMCS and vocabulary or matrix reasoning in males, controlling for prenatal exposure to maternal use of alcohol in pregnancy, birth weight and current smoking status
Bold = P < 0.05
PLEs Psychotic-like Experiences

ISSN: 1471-244X