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Table 2 Estimated mean outcome differences between treatment arms at end of treatment and follow-up

From: A pragmatic randomised multi-centre trial of multifamily and single family therapy for adolescent anorexia nervosa

 

End of treatment (12 months post randomisation)

Follow-up (18 months post randomisation)

 

Mean group difference

(95% CI)

Test

Standardised Coefficient

Mean group difference

(95% CI)

Test

Standardised Coefficient

Binary MR

2.55a (1.17, 5.52)

t = 2.36 p = 0.018

-

2.01a (0.91, 4.49)

t = 1.72 p = 0.086

-

%mBMI

2.24 (−0.47, 4.95)

t = 1.62 p = 0.105

0.37b

4.11 (0.98, 7.24)

t = 2.57 p = 0.010

0.68b

BMI

0.40 (−0.15, 0.94)

t = 1.43 p = 0.15

0.37b

0.74 (0.12, 1.36)

t = 2.35 p = 0.019

0.60b

EDE (restraint)

0.45 (−0.22, 1.11)

t = 1.33 p = 0.185

0.26b

0.45 (−0.26, 1.15)

t =1.25 p = 0.213

0.26b

EDE (eating concerns)

0.14 (−0.46, 0.73)

t = 0.44 p = 0.659

0.087b

0.18 (−0.42, 0.78)

t = 0.59 p = 0.559

0.12b

EDE (shape concerns)

0.54 (−0.18, 1.26)

t =1.48 p = 0.139

0.30b

0.56 (−0.20, 1.31)

t = 1.44 p = 0.150

0.30b

EDE (weight concerns)

0.44 (−0.27, 1.14)

t = 1.22 p = 0.223

0.23b

0.49 (−0.31, 1.29)

t =1.21 p = 0.226

0.26b

BDI

2.91 (−3.10, 8.91)

t = 0.95 p = 0.342

0.20b

2.14 (−4.16, 8.44)

t = 0.67 p = 0.504

0.15b

RSE

−1.09 (−3.91, 1.73)

t = −0.76 p0.447

−0.16b

0.5 (−2.45, 3.45)

t = 0.33 p = 0.739

0.08b

ECI - Negative

−2.22 (−17.1, 12.6)

t = −0.30 p = 0.766

−0.07b

-

-

-

ECI - Positive

0.71 (−2.07, 3.49)

t = 0.51 p = 0.612

0.08b

-

-

-

CSQ - Young Person

−1.14 (−3.73, 1.45)

t = −0.88 p = 0.382

−0.22c

-

-

-

CSQ - Parent

0.64 (−1.51, 2.79)

t = 0.5962 p = 0.556

0.13c

-

-

-

  1. Results are derived using multiple imputation with 100 imputations
  2. Abbreviations: MR Morgan Russell Scale, %mBMI a percentage of median Body Mass Index for young people of the same height, age and sex, EDE Eating Disorder Examination, BDI Beck Depression Inventory, RSE Rosenberg Self Esteem Scale, ECI Experience of Caregiving Inventory, CSQ Client Satisfaction Questionnaire
  3. athe effect is expressed as a marginal odds ratio (OR); The conditional OR was 4.57 (95% CI 1.28, 16.44) at 12 m and 3.16 (95% CI 0.84, 11.82) 18 m
  4. bstandardised coefficients were derived from dividing estimated difference by the standard deviation of the outcome variable at baseline
  5. cstandardised coefficients were derived from dividing difference scores by the standard deviation of the control group (FT-AN)