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Table 2 Serum and membrane lipids, patients and healthy controls, case–control and longitudinal data

From: Lipid profiles in schizophrenia associated with clinical traits: a five year follow-up study

 

Patients T1

Patients T2

Healthy controls T1

Healthy controls T2

n = 55

n = 55

n = 20

n = 51

PUFA

434 (171,507)

471 (440,513)***

478 (446,495)***

470.0 (437,508)

LCPUFA

283 (89,337)

308 (291,334)***

307 (293,330)***

306 (287,336)

S-cholesterol

5.00 ± 1.12

5.36 ± 1.20

¤

5.05 ± 0.84

S-triglyceride

1.50 (0.80,2.48)###

1.33 (0.95,2.66)###

¤

0.85 (0.59,1.12)

  1. ***P <0.001 vs. patients T1, ### P < 0.001 vs. healthy controls T2
  2. ¤not measured
  3. Serum cholesterol: normally distributed, mean ± standard deviation
  4. Serum triglyceride, PUFA, LCPUFA: non-normally distributed, median (25,75 percentiles)
  5. Patients T1 vs patients T2: Wilcoxon signed rank test
  6. Patients T1 and T2 vs healthy controls T1: Mann–Whitney test
  7. Healthy control T1 vs healthy controls T2: Wilcoxon signed rank test
  8. PUFA = omega-3 + omega-6 polyunsaturated fatty acids in red blood cells
  9. LCPUFA = omega-3 + omega-6 PUFA with 20 or more carbon atoms in red blood cells