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Table 3 Results pertaining to the only molecular pathway that was replicated in both samples (N tot. molecular pathways = 7) for the response phenotype

From: Genome-wide association study of antidepressant response: involvement of the inorganic cation transmembrane transporter activity pathway

  

Korean sample

STAR*D

GO ID

Pathway name

SNPs with p < 0.05

SNPs (tot N)

Permuted p

SNPs with p < 0.05

SNPs (tot N)

Permuted p

  

True

False

/

True

False

/

GO:0022890

Inorganic cation transmembrane transporter activity

478 (6 %)

7053 (93 %)

7531

2.9e-5

123 (8 %)

1317 (91 %)

1440

0.001

  1. True/False are referred to the number (and percentage) of SNPs showing association with p < 0.05 in the considered subset. The expected number (due to chance) of N true corresponds to 5 % of the total