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Table 1 Characteristics of major depressive disorder (MDD) and healthy control (HC) groups

From: The influence of 5-HTTLPR and Val66Met polymorphisms on cortical thickness and volume in limbic and paralimbic regions in depression: a preliminary study

Characteristics

MDD

HC

N

43

15

Sex (F/M)

26/17

8/7

Age (yrs.)

30.3 ± 8.1

36.6 ± 11.1

5-HTTLPR polymorphysima

LA/LA homozygotes = 8; S/S homozygotes = 14; S/LA heterozygotes = 20

LA/LA homozygotes = 5; S/S homozygotes = 3; S/LA heterozygotes = 7

Val66Met

Val/Val homozygotes = 35; Met/- carriers = 8 (Met/Met = 1; Val/Met = 7)

Val/Val homozygotes = 10; Met carriers = 5

Baseline HAMD17

21.4 ± 4.2

-

Duration of current MDE (yrs.)

4.4 ± 5.2

-

MDD onset (yrs.)

24.5 ± 10.9

-

  1. HAMD 17 Hamilton depression rating scale, MDD major depressive disorder
  2. Means ± SDs presented
  3. aS/S homozygotes: S/S, LG/S & LG/LG; S/LA heterozygotes: LA/S & LA/LG