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Table 2 Partial correlations between resting state thalamic networks and AUS/DUS rated cannabis use severity, frequency, and age at onset of cannabis use in the CHR and healthy control groups

From: Evaluating the impact of cannabis use on thalamic connectivity in youth at clinical high risk of psychosis

X

Y

Z

Hemisphere

Anatomical landmark

Severity

Frequency

Age at onset of cannabis use

CHR

HC

CHR

HC

CHR

HC

n = 162

n = 105

n = 162

n = 105

n = 99

n = 38

−31

−67

−43

Left

Cerebellum

0.01 (0.96)

0.01 (0.99)

−0.01 (0.89)

0.04 (0.83)

0.21 (0.04)

0.13 (0.47)

31

42

31

Right

Lateral prefrontal cortex

0.09 (0.28)

−0.16 (0.36)

0.14 (0.09)

−0.23 (0.19)

0.18 (0.08)

0.11 (0.55)

2

21

36

Midline

Anterior cingulate gyrus

−0.03 (0.68)

−0.08 (0.65)

−0.04 (0.63)

−0.08 (0.65)

0.16 (0.16)

0.20 (0.25)

−35

−23

58

Left

Sensory/ motor cortex

0.03 (0.73)

−0.06 (0.74)

−0.02 (0.79)

−0.07 (0.69)

0.26 (0.01)

0.10 (0.58)

19

−27

70

Right

Sensory/ motor cortex

0.03 (0.75)

0.12 (0.50)

−0.01 (0.87)

0.02 (0.91)

0.23 (0.03)

0.10 (0.59)

  1. Note. AUS/DUS Alcohol and drug use scale. CHR Clinical high risk, HC healthy control. Age, alcohol use and tobacco use have been entered as covariates. Results expressed as Pearson’s correlations with corresponding p-value in brackets. Significant results are bolded