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Table 1 Case studies of aripiprazole induced-tardive dystonia

From: Remission of irreversible aripiprazole-induced tardive dystonia with clozapine: a case report

 

Oommen et a.l. [12]

Lungu et al. [10]

Pinninti et al. [13]

Matsuda et al. [11]

Lungu et al. [10]

Sato et al. [15]

Friedman [14]

Sex

Female

Female

Male

Female

Male

Male

Female

Age

25

19

35

23

62

19

53

Diagnosis

Schizoaffective disorder

Anxiety disorder & violent outburst

Schizoaffective disorder

Schizophrenia

Post- traumatic stress disorder

Schizophrenia

Depression

Involved body part

Trunk (lumbar)

Head & trunk

Trunk (thoracic)

Larynx

Periocular area, neck

Wrist, elbow, shoulder

Trunk, pelvis

Reversibility

(+)

(+)

(+)

(+)

(−)

(−)

(−)

Effective treatment

Trihexyphenidyl

(−)

(−)

Quetiapine

Deep Brain Stimuationa

 

Tetrabenazineb

Duration of aripiprazole medication

2 months

3 years

About 8 weeks

7 months

18 months

8 months

2 years

Previous antipsychotics use

(+)

Drug naïve

(+)

(+)

Drug naïve

(+)

Drug naïve

Examinations

(−)

(−)

(−)

Lab, brain MRIc

(−)

Lab, brain MRIc

(−)

  1. aUnresponsive to trihexyphenidyl, clonazepam, baclofen, and botulinum
  2. bPartially effective
  3. cResults: normal