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Table 4 Relationship between baseline insight, adherence and therapeutic relationship and CGI and GAF at endpoint (all patients)

From: Relationship of insight with medication adherence and the impact on outcomes in patients with schizophrenia and bipolar disorder: results from a 1-year European outpatient observational study

 

Univariate relationship

(correlation coefficient)

Regression analysis coefficient (95 % CI)

Baseline value

CGI

GAF

CGI

GAF

SUM1

0.12#

−0.18#

0.13 (0.06; 0.20)#a

−1.76 (−2.69; −0.84)#a

SUM2

0.14#

−0.16#

0.14 (0.07; 0.22)#a

−1.31 (−2.37; −0.25)*a

SUM3

0.09*

−0.13#

0.08 (−0.02; 0.17)a

−0.48 (−1.81; 0.84)a

MARS

−0.07

0.14#

0.02 (−0.01; 0.05)b

−0.02 (−0.47;0.44)b

WAI

−0.15+

0.23#

−0.01 (−0.01; −0.004)#b

0.13 (0.08; 0.17)#b

  1. As higher ratings in some scales mean better outcomes and lower ratings in other scales mean better outcomes, the signs of Pearson correlation coefficients have been modified so that positive coefficients mean improvement in one variable is positively correlated with improvement in the other
  2. CGI clinical global impression, GAF global assessment of functioning, SUM1 unawareness of having a mental disorder, SUM2 unawareness of response to medication, SUM3 unawareness of the need of medication, MARS medication adherence rating scale, WAI working alliance inventory
  3. #p < 0.001
  4. *p < 0 .05
  5. +p < 0.01
  6. aAdjusted for country, age, sex, MARS and WAI
  7. bAdjusted for country, age, sex, MARS, WAI and SUM1