Skip to main content

Table 3 Clozapine co-prescribing with antipsychotics and mood stabilisers (ranked in descending order of percentage median improvement change on MSE symptom severity scores)

From: Skating on thin ice: pragmatic prescribing for medication refractory schizophrenia

Augmentation Patients Median clozapine dose (mg) Clozapine interquartile range (mg) Median co-prescribed dose (mg) Co-prescribed dose interquartile range (mg) Median improvement % Improvement IQR %
Sodium valproate 22 550.0 225.0 1500 800.0 62.5 21.1
Lithium 16 375.0 375.0 800 100.0 56.9 36.8
Amisulpride 26 500.0 237.5 300 200.0 53.0 39.5
Quetiapine 13 550.0 159.4 400 212.5 51.0 30.5
Lamotrigine 14 337.5 262.5 200 37.5 43.7 32.0