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Table 1 Measures

From: The Effects of Stress on Cognitive Aging, Physiology and Emotion (ESCAPE) Project

Construct

Domain

Description

Measures

Stress

Chronic

Role and environmental stress, neighborhood security, discrimination

Wheaton Chronic Stress (WCS) Scale, Lifetime Discrimination Scale, Neighborhood Safety and Violence Scale [70–72]

Major events

Lifetime & recent exposure to major life events and trauma (e.g., bereavement, abuse)

Lifetime Adversity and Recent Life Event subscales of WCS [70]

Subjective

Perceived stressfulness of life over last month

Perceived Stress Scale [73]

Daily events

Exposure to daily hassles and stressors (e.g., arguments, deadlines, illness)

Adapted from Daily Inventory of Stressful Experiences [74]

URT

Event-related

Recurring thoughts about major stressor

Impact of Events Scale-Revised [75]

Dispositional

Tendency to ruminate or reflect

Rumination-Reflection Questionnaire [38]; White Bear Suppression Inventory [37]

Momentary

Experiencing recurring, unwanted, negative thoughts

Momentary Thought Questionnaire

Cognition

Laboratory

Working memory

Operation-span, Counting-span, Backward letter span

episodic memory

AVLT, Paired-associates, Card Memory Task

processing speed

Letter, Number and Symbol matching

fluid and crystallized intelligence

Ravens Progressive Matrices; Vocabulary

 

Ambulatory

Working memory (verbal, spatial), processing speed

See Fig. 2

Biomarkers

Laboratory

Basal inflammatory markers

Plasma cytokines: IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, TNF-α, IFN-γ, GM-CSF; Plasma CRP

Ambulatory

LPS-stimulated cytokines

Plasma cytokines: IL-1β, IL-6, IL-8, IL-10, TNF-α, GM-CSF

Stress-related hormones

Salivary cortisol sampled 4 times per day for the first 5 days of each burst

Plasma cortisol; Plasma DHEAS

Physical & Mental Health

Objective

Metabolic risk indicators

Lipid profiles; insulin; glucose

 

Subjective

Physical functioning, medical history, medication use, anxiety, depression, mood over last month, life satisfaction

PROMIS Physical Function Short Form-A, PROMIS Emotional Distress – Anxiety – Short Form 7-A, PROMIS Depression Short From 8-A, Positive and Negative Affect Schedule, Satisfaction with Life Scale [64, 76, 77]

Risk & Protective Factors

Risk

Neuroticism, social isolation, childhood adversity, anger

International Personality Item Pool (IPIP) Neuroticism subscale, PROMIS Social Isolation – Short Form-6a, Childhood Adversity subscale from WCS, State-Trait Anger Expression Inventory [70, 78, 79]

 

Protective

Conscientiousness, social support, positive events, optimism, adult temperament, mindfulness

IPIP Conscientiousness subscale, PROMIS Emotional, Informational, and Instrumental Social Support – Short Forms-6a, Pleasant Events Schedule, Life Orientation Test, Adult Temperament Questionnaire, Five Facet Mindfulness Questionnaire [64, 78, 80–83]

Demographics

Person

Age, race, ethnicity, gender

Demographic questionnaire

 

Context

income, work status, marital status, education

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