Figure 1From: Lithium as a rescue therapy for regression and catatonia features in two SHANK3 patients with autism spectrum disorder: case reportsClinical Global Improvement - Severity and - Improvement scale at different time points of the follow-up of patient 1. The Clinical Global Impression scale (CGI) has two components: the CGI-Severity (CGI-S), which is a seven-point scale rating severity of illness (1-normal to 7-extremely ill) and the CGI-Improvement (CGI-I), which assesses the change of patient’s illness since the initiation of treatment (1-very much improved to 7-very much worse) [18].Back to article page