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Table 1 Basic data of healthy controls and schizophrenia patients

From: Asymmetric dimethylarginine in somatically healthy schizophrenia patients treated with atypical antipsychotics: a case–control study

 

Control (N = 40)

Schizophrenia (N = 40)

P -value

Gender (M/F)

20/20

20/20

1.0

Age (years)

31.4 ± 9.8

33.0 ± 10.7

0.49

Smoker (%)

21

55

0.002

Cigarettes per day (if smoker)

8.1 ± 6.4

18.1 ± 11.3

0.03

Alcohol (drinks per week)

5 (2–10)

1 (0–5)

0.002

Exercise (hours per week)

3 (1–5)

0 (0–2)

<0.001

Body Mass Index

25.1 ± 3.8

27.2 ± 5.7

0.06

Waist-hip ratio

0.80 ± 0.07

0.89 ± 0.08

<0.001

Systolic blood pressure (mmHg)

124.6 ± 11.6

127.1 ± 12.2

0.34

Diastolic blood pressure (mmHg)

78.9 ± 8.6

78.5 ± 7.3

0.37

Pulse (min−1)

64.6 ± 10.6

81.0 ± 14.3

<0.001

Metabolic Syndrome (y/n)a

2/37

11/27

<0.001

Perceived Stress Scale score

7.7 ± 4.2

22.3 ± 6.7

<0.001

Childhood Abuse and Trauma Scale score

11 (8–20)

39 (17–67)

<0.001

Total cholesterol (mmol/L)

4.7 ± 0.8

4.9 ± 0.9

0.44

HDL cholesterol (mmol/L)

1.5 ± 0.4

1.4 ± 0.4

0.40

LDL cholesterol (mmol/L)

2.8 ± 0.6

2.8 ± 0.8

0.75

Triglycerides (mmol/L)

0.90 (0.70-1.15)

1.25 (0.76-2.00)

0.02

Glucose (mmol/L)

5.2 ± 0.4

5.1 ± 0.6

0.48

HbA1c (mmol/L)

5.2 ± 0.3

5.4 ± 0.4

0.01

Plasma Creatinine (μmol/L)

73 ± 16

69 ± 14

0.20

CRP (mg/L)

1 (1–2)

2 (1–4)

0.002

  1. Numbers are means ± standard deviation or medians (interquartile range). Data are analyzed with t-tests, Mann Whitney tests or Chi-squared tests, as appropriate. aAs defined in [25] (because of a few participants with missing values, the sum does not reach 40 in each group). Abbreviations:HDL High-density lipoprotein; LDL Low-density lipoprotein, HbA1c Glycated hemoglobin. CRP: C-reactive protein.