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Table 1 Measurements of primary, secondary and tertiary objectives: drinking behavior, mediators, moderators and predictors and quality of life

From: A multi-site randomized study to compare the effects of Eye Movement Desensitization and Reprocessing (EMDR) added to TAU versus TAU to reduce craving and drinking behavior in alcohol dependent outpatients: study protocol

  Outcome Measurement Baseline screening T0 T1 T2 T3
   -interview (i)   Pretreatment Posttreatment 1 month FU 6 months FU
   -self-report (s)      
   -reaction time (r)      
   -bloodsample (b)      
1 Recent and lifetime use, indications for psychiatric or medical evaluation, addiction treatment history and current abuse or dependence (DSM-IV) MATE (part 1–4) (i) X     
2 Comorbid psychiatry (DSM-IV) MINI-plus (i) X     
3 Motivation to change RCQ-D (s)   X    
4 Harmful alc. use AUDIT (30 d) (s)   X X X X
5 Self-efficacy SELD (s)   X X X X
6 Health outcome EQ-5D (s)   X X X X
7 Quality of life CRA-HS (s)   X X X X
8 Alcohol craving PACS (s)   X X X X
9 Desire thinking DTQ (s)   X X X X
10 Pos. and neg. affect PANAS-SF (s)   X X X X
11 Rumination PTQ (s)   X X X X
12 Drinking behavior TLFB (30 d) (i)   X X X X
13 Alcohol attentional bias Alcohol Stroop (r)   X X X X
14 Alcohol implicit assoc. Valence IAT (r)   X X X X
15 Biomarkers chron. alc. use GGT + CDT (b)   X X X X
  1. AUDIT Alcohol Use Disorders Identification Test, CDT carbohydrate-deficient transferrin, CRA-HS Community Reinforcement Approach Happiness Scale, DSM-IV Diagnostic and Statistical Manual – 4th ed., DTQ Desire Thinking Questionnaire, EQ-5D™ EuroQol - 5 dimensions, GGT serum γ-glutamyltransferase, IAT Implicit Association Task, M.I.N.I.-plus M.I.N.I. International Neuropsychiatric Interview-Plus, PACS Penn Alcohol Craving Scale, PANAS-SF Positive And Negative Affect Schedule – Short Form, PTQ Perseverative Thinking Questionnaire, RCQ-D Readiness to Change Questionnaire - Dutch version, SELD Self-Efficacy List for Drug users, TLFB Timeline Followback.