Association between brain-derived neurotrophic factor genetic polymorphism Val66Met and susceptibility to bipolar disorder: a meta-analysis

Table 1 Descriptive characteristics of included association studies between BDNF gene Val66Met polymorphism and bipolar disorders

Study	Year	Ancestry	Diagnostic criteria	Patient’s phenotype	Cases	Controls	Case Val	Controls Val
Hong et al. [38]	2003	Han Chinese	DSM-IV	BPD	108	392	118	406
Nakata et al. [39]	2003	Japanese	DSM-IV	BPI + BPII	130	190	152	220
Kunugi et al. [40]	2004	Japanese	DSM-IV	BPI + BPII	519	588	615	702
Oswald et al. [41]	2004	Caucasian	DSM-IV	BPAD	108	158	166	247
Skibinska et al. [42]	2004	Caucasian	DSM-IV	BPAD	352	375	588	613
Lohoff et al. [43]	2005	Caucasian	DSM-IV	BPI	621	998	1020	1576
Neves-Pereira et al. [44]	2005	Caucasian	DSM-IV	BPAD	263	350	417	547
Schumacher et al. [45]	2005	Caucasian	DSM-IV	BPAD	281	1097	456	1778
Green et al. [46]	2006	Caucasian	DSM-IV	BPI + BPII + Rapid-cycling BPD	1093	2100	1808	3404
Liu et al. [47]	2007	Han Chinese	ICD-10	BPAD	100	100	114	99
Tramontina et al. [48]	2007	Caucasian	DSM-IV	BPI	114	137	183	230
Kim et al. [49]	2008	Korean	DSM-IV	BPD	169	251	186	268
Tang et al. [50]	2008	Han Chinese	DSM-IV	BPD	197	208	238	235
Vincze et al. [51]	2008	Caucasian	DSM-IV	BPD	336	313	532	473
Ye et al. [52]	2009	Han Chinese	DSM-IV	BPD	222	357	217	367
Hosang et al. [53]	2010	Caucasian	ICD-10	BPD	488	598	780	983
Xu et al. [54]	2010	Han Chinese	DSM-IV	BPI + BPII	498	501	525	546
Min et al. [55]	2012	Korean	DSM-IV	BPD	184	214	222	245
Wang et al. [56]	2012	Han Chinese	DSM-IV	BPI + BPII	337	386	341	436
Chang et al. [30]	2013	Han Chinese	DSM-IV	BPI + BPII	967	349	962	361
Pae et al. [57]	2012	Korean	DSM-IV	BPD	132	170	150	197

ISSN: 1471-244X