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Table 4 Suicide deaths and rates over time by mood stabilizer treatment over briefer time periods (0–90 and 0–180 days)

From: Suicide risk in Veterans Health Administration patients with mental health diagnoses initiating lithium or valproate: a historical prospective cohort study

A. Intent-to-Treat Analyses
  All Patients Initiating Treatment (Intent-to-Treat Cohort)   
  Patients Initiating Lithium Patients Initiating Valproate   
Follow-up Time Patients, No. Suicide Deaths, No. Rate (per 106 person-days) Patients, No. Suicide Deaths, No. Rate (per 106 person-days) Conditional Odds Ratio (95% CI) Rate Ratio
0-90 days 21194 18 9.35 21194 19 9.87 0.95a (0.50-1.81) 0.95
0-180 days 21194 39 10.20 21194 25 6.54 1.56b (0.94-2.58) 1.56
B. Findings Stratified by Initial Treatment Status
  During Exposure to Initial Treatmentc   
  Patients Initiating Lithium Patients Initiating Valproate   
Follow-up Time Patients, No. Suicide Deaths, No. Rate (per 106 person-days) Patients, No. Suicide Deaths, No. Rate (per 106 person-days) Conditional Odds Ratio (95% CI) Rate Ratio
0-90 days 21194 15 10.00 21194 17 11.30 0.88d (0.44-1.77) 0.88
0-180 days 21194 17 7.99 21194 17 7.93 1.00e (0.51-1.96) 1.01
  During Period After Stopping/Modifying Initial Treatmentf   
  Patients Initiating Lithium Patients Initiating Valproate   
Follow-up Time Patients, No. Suicide Deaths, No. Rate (per 106 person-days) Patients, No. Suicide Deaths, No. Rate (per 106 person-days) Odds Ratio (95% CI) Rate Ratio
0-90 days 11227 3 6.98 11185 2 4.75 1.49g (0.25-8.95) 1.47
0-180 days 16138 22 13.00 15958 8 4.78 2.72h,i (1.21-6.11) 2.72