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Table 3 Logistic regression models of the association between the extent of chronic pain and probable bipolar disorder, relative to probable major depressive disorder

From: Chronic multisite pain in major depression and bipolar disorder: cross-sectional study of 149,611 participants in UK Biobank

Model

 

OR (95% CI*)

P value^

P value^^

1. No adjustments (n = 149,612)

No chronic pain

1

 

<0.001

1 site

1.04 (0.92, 1.18)

0.520

2-3 sites

1.25 (1.10, 1.43)

0.001

4-7 sites

1.42 (1.13, 1.77)

0.002

Widespread pain

1.92 (1.44, 2.57)

<0.001

2. Adjusted for sex, age, ethnicity, deprivation and employment status (n = 147,463)

No chronic pain

1

 

<0.001

1 site

1.02 (0.90, 1.17)

0.724

2-3 sites

1.18 (1.03, 1.34)

0.018

4-7 sites

1.16 (0.92, 1.47)

0.210

Widespread pain

1.34 (0.99, 1.83)

0.061

3. Adjustments as for 2. plus BMI, smoking status and frequency of alcohol consumption (n = 145,945)

No chronic pain

1

 

<0.001

1 site

1.01 (0.88, 1.15)

0.898

2-3 sites

1.15 (1.01, 1.32)

0.039

4-7 sites

1.11 (0.88, 1.41)

0.372

Widespread pain

1.32 (0.97, 1.81)

0.079

4. Adjustments as for 3. plus additional long term condition morbidity count (n = 145,518)

No chronic pain

1

 

<0.001

1 site

1.01 (0.88, 1.15)

0.881

2-3 sites

1.16 (1.01, 1.33)

0.035

4-7 sites

1.12 (0.88, 1.43)

0.339

Widespread pain

1.34 (0.97, 1.83)

0.072

  1. *Relative to the probable MDD group.
  2. ^P-value for each level of chronic pain.
  3. ^^P-value for overall model.
  4. OR – odds ratio; 95% CI – 95% confidence interval; BMI – body mass index.