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Table 2 Unadjusted and adjusted ORs from logistic regression for association between statin prescription and subsequent diagnosis of depression between 2006-2008 ( n= 4,607,990)

From: Statin use and risk of depression: a Swedish national cohort study

 

Unadjusted OR

95% CI

p-value

Age-adjusted OR

95% CI

p-value

Adjusted OR a

95% CI

p-value

Statin prescriptions

         

Any statin

0.92

0.89-0.96

<0.001

0.92

0.88-0.95

<0.001

0.95

0.91-0.99

0.016

Simvastatin

0.91

0.87-0.95

<0.001

0.91

0.87-0.94

<0.001

0.93

0.89-0.97

0.001

Pravastatin

0.86

0.71-1.04

0.120

0.85

0.70-1.03

0.090

0.90

0.74-1.09

0.268

Fluvastatin

0.92

0.61-1.37

0.677

0.91

0.61-1.36

0.643

0.98

0.65-1.46

0.914

Atorvastatin

1.02

0.93-1.13

0.632

1.03

0.94-0.97

0.507

1.11

1.01-1.22

0.032

Rosuvastatin

1.08

0.82-1.43

0.578

1.12

0.84-1.47

0.443

1.21

0.92-1.60

0.177

  1. CI = confidence interval; OR = odds ratio.
  2. aThe model includes prescription of statin medication (any statin, and by individual statins) and the following variables as covariates: gender, age (40-49, 50-59, 60-69, 70+), marital status, education (three levels), family income (quartiles), hospitalisation for cardio-pulmonary disease, hospitalisation for alcoholism, hospitalisation for coronary heart disease, and region (large cities, Southern, Northern).