Skip to main content

Table 3 Validation studies and results of articles from the systematic review

From: Systematic review and assessment of validated case definitions for depression in administrative data

Author Country N Year of data collection Administrative database Reference standard ICD codes Prevalence (%) Sensitivity (%) Specificity (%) PPV (%) NPV (%)
Alaghehbandan (2012) Canada 510 1995-2008 Provincial Hospital Separation Database; Provincial fee-for-service physician claims database Electronic Medical Record and Medical Chart Review ICD-9: 311; ICD-10-CA: F32.0-F32.3, F32.8, F32.9, F33.0-F33.4, F33.8, F34.1 NR     
       ≥ 1 Hospital OR ≥2 Physician within 1 Year   70.0 93.8 91.7 76.0
       ≥ 1 Hospital OR ≥2 Physician within 2 Years   75.1 93.0 91.3 79.1
       ( ≥1 Hospital OR ≥1 PSY) OR ≥2GP within 1 Year   73.1 93.4 91.6 77.9
       ( ≥1 Hospital OR ≥1 PSY) OR ≥2 GP within 2 Years   77.5 93.0 91.6 80.7
       ( ≥1 Hospital OR ≥1 PSY) OR ≥3 GP within 3 Years   69.6 93.4 91.2 75.7
Noyes (2011) USA 1,605 1998-2002 Medicare Previous MDE, GDS, or MINI-MDE ICD-9: 296.20-.24, 296.30-.34 18% based on MINI     
      MDE at baseline- claims diagnoses at 6 months before & after baseline    14.13 95.61 41.05 83.72
      MDE at baseline- claims diagnoses at 12 months before & after baseline    18.12 93.45 37.31 84.14
      GDS ≥6 at baseline- claims diagnoses at 6 months before & after baseline    9.96 95.60 55.42 65.90
      GDS ≥6 at baseline- claims diagnoses at 12 months before & after baseline    12.69 93.26 50.86 66.03
      MINI-MDE at baseline- claims diagnoses at 6 months before and after baseline ICD-9: 296.20-.24, 296.30-.34, 300.4, 309.0, 311   33.70 82.12 28.97 85.12
      MINI-MDE at baseline- claims diagnoses at 12 months before and after baseline    46.38 74.98 28.51 86.67
      GDS ≥6 at baseline- claims diagnoses at 6 months before and after baseline    27.92 83.35 47.96 67.79
      GDS ≥6 at baseline- claims diagnoses at 12 months before and after baseline    39.57 77.42 49.07 69.98
      GDS ≥11 at baseline- claims diagnoses at 6 months before and after baseline ICD-9: 296.20-.24, 296.30-.34   55.06 73.32 13.07 95.73
      GDS ≥11 at baseline- claims diagnoses at 12 months before and after baseline    42.48 78.57 40.37 80.00
      2 positive MINI-MDEs at baseline and at 12 months- claims diagnoses at 12 months before and after baseline    46.63 74.69 12.11 94.89
Singh (2006) USA 40,508 1996-1998 Veterans Integrated Service Network Self-report of depression ICD-9: 296.xx, 300.4, 301.1x, 298, 311 NR 34.00 97.00 83.00 79.00
  1. PPV: Positive predictive value; NPV: Negative predictive value; MDE: Major Depressive Episode; MINI-MDE: Mini-International Neuropsychiatric Interview-Major Depressive Episode; GDS: Geriatric Depression Scale; NR: Not reported; PSY: Psychiatrist visit; GP: General Practitioner visit.