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Table 1 Psychiatric symptoms and thyroid axis hormone concentrations in acute psychotic patients before and after treatment, and in healthy blood donor controls, Mean ± SD

From: Thyroid axis function after in-patient treatment of acute psychosis with antipsychotics: a naturalistic study

 

Patients, N = 86

p (pairedt-test)

Controls

p (unpairedt-test)

 

Before treatment

After treatment

 

N = 109

vspatients before treatment

vspatients after treatment

Brief Psychiatric Rating Scale

39 ± 8

19 ± 6

p < 0.001

-

-

-

Free triiodothyronine (pmol/l)

5.2 ± 1.0

4.5 ± 1.0

p < 0.001

5.2 ± 0.9

0.70

<0.001

Free thyroxine (pmol/l)

17.9 ± 3.1

16.8 ± 2.6

p = 0.002

16.8 ± 2.2

0.004

0.89

Thyroid stimulating hormone (μIU/ml)

1.68 ± 0.9

2.07 ± 1.4

p = 0.016

1.40 ± 0.7

0.016

<0.001