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Table 1 Summary of the included studies in the meta-analysis

From: Vortioxetine in the treatment of adult patients with major depressive disorder: a meta-analysis of randomized double-blind controlled trials

Authors

Year

Duration

Group1/Sample

Group 2/Sample

Group 3/Sample

Group 4/Sample

Group 5/Sample

Alvarez E et al. [10]

2011

6 weeks

Vortioxetine 5 mg/108

Vortioxetine 10 mg/100

Venlafaxine/113

Placebo/105

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Baldwin DS et al. [14]

2012

8-week

Vortioxetine 2.5 mg/155

Vortioxetine 5 mg/155

Vortioxetine 10 mg/151

Duloxetine 60 mg/149

Placebo/145

Mahableshwarkar AR et al. [16]

2013

8 weeks

Vortioxetine 2.5 mg/146

Vortioxetine 5 mg/153

Duloxetine 60 mg/149

Placebo/149

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Katona C et al. [11]

2012

8 weeks

Vortioxetine 5 mg/day/154

Duloxetine/147

Placebo/145

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Jain R et al. [15]

2013

6 wks

Vortioxetine 5 mg/300

Placebo/300

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Boulenger JP et al. [12]

2013

8 weeks

Vortioxetine 15 mg/151

Vortioxetine 20 mg/151

Duloxetine/147

Placebo/158

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Henigsberg N et al. [13]

2012

8 wks

Vortioxetine 1 mg/124

Vortioxetine 5 mg/129

Vortioxetine 10 mg/122

Placebo/128

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