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Table 3 Adjuvant interventions - added to antipsychotics other than clozapine

From: Treatment resistant schizophrenia: a comprehensive survey of randomised controlled trials

Name of intervention Number Cochrane review
Studies Participants
Added to specific antipsychotic
Olanzapine  
  Antipsychotic Chlorpromazine 1 39  
  Sulpride 2 114  
Risperidone  
  Antipsychotic Quetiapine 1 144  
Chlorpromazine  
  Movement disorder drugs LDOPA 1 8  
Haloperidol     
  Serotonin 5-HT3 receptor antagonist Ondansetron 1 121  
Added to unspecified antipsychotic     
  Amino Acids Glycine 3 50 [27]
  Serine 1 39 [27]
  Antidepressants Citalopram 1 18  
  Escitalopram 1 30  
  Mianserin 1 18  
  Sertraline 1 77  
  Anticonvulsants and mood stabilisers Valproate 2 140 [23]
  Carbamazepine 3 79 [28]
  Topiramate 2 86  
  Lamotrigine 1 38 [24]
  Lithium 5 227 [25]
  Antimicrobials D-Cycloserine 2 35 [27]
  Ketoconazole 2 24  
  Herbal Ning Xin Tang 1 60  
  Ginkgo Biloba 1 82  
  Yi Gan San 1 59  
  Movement disorder drugs Apomorphine 1 18  
  Tetrabenazine 1 41  
  Opioid acting drugs Methadone 1 7  
  Salt or ester of benzoic acid Benzoate 1 60  
  Histamine H2 receptor antagonist Famotidine 1 30  
  Oestrogen receptor antagonist Tamoxifem 1 26