Quetiapine IR | Quetiapine XR | Total | |
---|---|---|---|
Characteristic | (N = 659) | (N = 571) | (N = 1230) |
Gender (male), N (%) | 337 (51.1) | 279 (48.9) | 616 (50.1) |
Age (years), mean (SD) | 42.8 (13.7) | 42.4 (13.3) | 42.7 (13.5) |
Years in education, mean (SD) | 9.9 (3.9) | 10.3 (3.9) | 10.1 (3.9) |
Currently employed, N (%) | 178 (27.0) | 164 (28.7) | 342 (27.8) |
Cohabitation (lives accompanied), N (%) | 519 (78.8) | 421 (73.7) | 940 (76.4) |
Alcohol abuse/dependence,* N (%) | 113 (17.1) | 104 (18.2) | 217 (17.6) |
Drug abuse/dependence,* N (%) | 46 (7.0) | 44 (7.7) | 90 (7.3) |
Any relevant psychiatric medical history, N (%) | 75 (11.4) | 53 (9.3) | 128 (10.4) |
Any relevant non-psychiatric medical history, N (%) | 158 (24.0) | 134 (23.5) | 292 (23.7) |
Family history of mental illness, N (%) | 190 (28.8) | 189 (33.1) | 379 (30.8) |
Time since first diagnosis to hospital admission (years), median | 5.7 | 6.3 | 5.9 |
Episode polarity diagnosis, N (%) | |||
Manic | 453 (68.7) | 352 (61.6) | 805 (64.5) |
Hypomanic | 18 (2.7) | 25 (4.4) | 43 (3.5) |
Depressive | 86 (13.1) | 63 (11.0) | 149 (12.1) |
Mixed | 36 (5.5) | 25 (4.4) | 61 (5.0) |
No other specified | 5 (0.8) | 5 (0.9) | 10 (0.8) |
Unknown | 61 (9.3) | 98 (17.2) | 159 (12.9) |
Previous hospital admission due to bipolar disorder, N (%) | 183 (27.8) | 160 (28.0) | 343 (27.9) |
Any suicide attempt since diagnosis, N (%) | 85 (12.9) | 74 (13.0) | 159 (12.9) |
Severity of index manic event, N (%) | |||
Mild | 22 (3.3) | 17 (3.0) | 39 (3.2) |
Moderate | 185 (28.1) | 155 (27.1) | 340 (27.6) |
Severe, without psychotic symptoms | 178 (27.0) | 166 (29.1) | 344 (28.0) |
Severe, with psychotic symptoms | 248 (37.6) | 202 (35.4) | 450 (36.6) |
Unavailable | 26 (3.9) | 31 (5.4) | 57 (4.6) |