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Table 3 Trials targeting the VC/VS region

From: Deep brain stimulation for treatment-refractory obsessive compulsive disorder: a systematic review

VC/VS

Reference

Responders (ratio)

Follow-up

Patients published elsewhere

Y-BOCS Reduction

Greenberg, 2006 [39]

4/8

36 months

 

35.5%

Greenberg, 2010* [40]

16/26

36 months

10 patients from Greenberg et al. [39], and five patients included in Nuttin et al. [23]

38.5%

Goodman, 2010* [41]

4/6

12 months

Five patients from Greenberg et al. [39]

91.3%

Tsai, 2012 [42]

2/4

15 months

 

53,4%

Mean

50%

  

41.5%

  1. VC/VS: ventral capsule/ventral striatum. Responders’ ratio: responders defined as 35% improvement in Y-BOCS score or more. Follow-up: latest follow-up reported. Patients included elsewhere: Number of patients of which the data has been reported before and corresponding publication. Y-BOCS reduction: mean reduction for new patients at latest follow-up or reduction range if individual data not available. *Data not included in pooled means due to missing information/republisheded data.
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BMC Psychiatry

ISSN: 1471-244X

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