Deep brain stimulation for treatment-refractory obsessive compulsive disorder: a systematic review

BMC Psychiatry

Table 2 Trials targeting the NAc region

NAc
Reference	Responders (ratio)	Follow-up	Patients included elsewhere	Y-BOCS Reduction
Aouizerate, 2004 [32]	1/1	15 months		52%
Plewnia, 2008 [33]	0/1	24 months		21.9%
Denys, 2010 [12]	9/16	8 months		46%
Franzini, 2010 [35]	1/2	24 months		38.2%
Huff, 2010 [31]	1/10	12 months		21.1%
Roh, 2012* [36]	4/4	24 months		45.7-79.5%
Barcia, 2013 [37]	2/2	3 months		43.9%
Corveleyn, 2013 [38]	1/1	22 months		63.9%
Mean	45.5%			37.8%

NAc: Nucleus accumbens. Responders’ ratio: responders defined as 35% improvement in Y-BOCS score or more. Follow-up: latest follow-up reported. Patients included elsewhere: Data Number of patients of which the data has been reported before and corresponding publication. Y-BOCS reduction: mean reduction for new patients at latest follow-up or reduction range if individual data not available. *Data not included in pooled means due to missing information.

ISSN: 1471-244X