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Table 1 Trials targeting the ALIC

From: Deep brain stimulation for treatment-refractory obsessive compulsive disorder: a systematic review

ALIC

Reference

Responders (ratio)

Follow-up

Patients included elsewhere

Y-BOCS Reduction

Gabriels, 2003 [24]

2/3

33 months

1 patient included in Nuttin, [13]

35.5%

Anderson & Ahmed, 2003 [25]

1/1

3 months

 

79.4%

Nuttin, 2003*[23]

3/6

31 months

3 patients included in Gabriels, [24]

17.6-72%

Abelson, 2005*[26]

2/4

23 months

 

0-73.3%

Servello, 2009 *[27]

2/4

51 months

 

8.7-60.5%

Mean

75%

  

46.5%

  1. ALIC: anterior limb of the internal capsule. Responders’ ratio: responders defined as 35% improvement in Y-BOCS score or more. Follow-up: latest follow-up reported. Patients included elsewhere: Number of patients of which the data has been reported before and corresponding publication. Y-BOCS reduction: mean reduction for new patients at latest follow-up or reduction range if individual data not available. *Data not included in pooled means due to missing information/republished data.
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BMC Psychiatry

ISSN: 1471-244X

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