From: Clinical and economic ramifications of switching antipsychotics in the treatment of schizophrenia
Characteristic | Patients continuing with their initial antipsychotics (N = 376) | Patients switching antipsychotics (N = 156) | p-value |
---|---|---|---|
Male, % | 66.5 | 51.9 | .002 |
Age, mean (SD), y | 42.6 (12.0) | 42.8 (12.8) | .877 |
Age of onset, mean (SD), y | 22.8 (10.3) | 22.6 (9.2) | .802 |
Unemployed | 79.0 | 78.9 | .971 |
Race, % | Â | Â | Â |
   Caucasian | 54.8 | 53.9 | .843 |
   African descent | 33.0 | 34.0 | .824 |
   Other | 12.2 | 12.2 | .986 |
Diagnosis, % | Â | Â | Â |
   Schizophrenia | 65.7 | 61.5 | .362 |
   Schizoaffective | 25.0 | 28.2 | .443 |
   Schizophreniform | 9.3 | 10.3 | .735 |
Comorbidities, % | Â | Â | Â |
   MDD | 13.3 | 14.1 | .805 |
   Anxiety | 6.1 | 3.2 | .171 |
   Substance abuse | 32.2 | 25.8 | .146 |
 | Patients continuing with their initial antipsychotics (N = 376) | Patients switching antipsychotics (N = 156) | p-value |
Baseline PANSS total, mean (SD) | 88.9 (20.6) | 84.5 (19.3) | .023 |
Hospitalization in prior year | 30.2 | 24.5 | .191 |