Treatment Group | Study Visit | |||||||
---|---|---|---|---|---|---|---|---|
VE | V2 | V5 | V8 | V9 | V12 | V15 | V18 | |
CGI-S | ||||||||
Combination | 1.80 (0.84) | 1.40 (0.55) | 1.60 (0.55) | 1.20 (0.45) | 1.80 (0.45) | 1.60 (0.55) | 1.40 (0.55) | 1.40 (0.55) |
Monotherapy | 2.46 (0.66) | 1.92 (0.86) | 1.46 (0.66) | 1.54 (0.66) | 1.38 (0.65) | 1.46 (0.52) | 1.54 (0.66) | 1.38 (0.51) |
Total | 2.28 (0.75) | 1.78 (0.81) | 1.50 (0.62) | 1.44 (0.62) | 1.50 (0.62) | 1.50 (0.51) | 1.50 (0.62) | 1.39 (0.50) |
CGAS | ||||||||
Combination | 79.20 (2.39) | 83.00 (2.74) | 81.00 (5.47) | 82.00 (5.70) | 79.00 (2.24) | 80.00 (6.12) | 83.00 (4.47) | 84.00 (2.24) |
Monotherapy | 73.54 (8.23) | 78.84 (7.68) | 79.23 (7.86) | 80.38 (7.21) | 82.38 (8.30) | 83.46 (3.15) | 82.69 (6.33) | 82.38 (3.84) |
Total | 75.11 (7.48) | 80.00 (6.85) | 79.72 (7.16) | 80.83 (6.69) | 81.44 (7.22) | 82.50 (4.28) | 82.77 (5.74) | 82.83 (3.48) |
MADRS | ||||||||
Combination | 9.40 (6.15) | 4.40 (2.88) | 4.20 (4.08) | 4.80 (4.76) | 6.60 (3.91) | 5.60 (2.88) | 3.00 (3.00) | 2.80 (2.28) |
Monotherapy | 9.15 (6.01) | 5.54 (6.03) | 3.85 (4.27) | 4.54 (3.62) | 3.15 (3.55) | 3.92 (3.01) | 3.46 (3.30) | 4.15 (3.84) |
Total | 9.22 (5.86) | 5.22 (5.28) | 3.94 (4.10) | 4.61 (3.82) | 4.11 (3.87) | 4.39 (2.99) | 3.33 (3.14) | 3.78 (3.47) |
YMRS | ||||||||
Combination | 0.60 (1.34) | 0.20 (0.45) | 2.20 (3.35) | 1.40 (1.67) | 2.40 (3.78) | 0.40 (0.55) | 0.40 (0.89) | 0.80 (0.84) |
Monotherapy | 1.92 (3.04) | 1.08 (1.04) | 0.77 (1.69) | 1.31 (2.06) | 0.85 (1.57) | 1.31 (1.84) | 1.00 (2.24) | 1.54 (2.11) |
Total | 1.56 (2.71) | 0.83 (0.98) | 1.17 (2.25) | 1.33 (1.91) | 1.28 (2.37) | 1.06 (1.62) | 0.83 (1.94) | 1.33 (1.84) |