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Table 2 Means (SD) of secondary outcome variables as a function of study visit and treatment group.

From: Maintenance treatment of adolescent bipolar disorder: open study of the effectiveness and tolerability of quetiapine

Treatment Group

Study Visit

 

VE

V2

V5

V8

V9

V12

V15

V18

CGI-S

Combination

1.80

(0.84)

1.40

(0.55)

1.60

(0.55)

1.20

(0.45)

1.80

(0.45)

1.60

(0.55)

1.40

(0.55)

1.40

(0.55)

Monotherapy

2.46

(0.66)

1.92

(0.86)

1.46

(0.66)

1.54

(0.66)

1.38

(0.65)

1.46

(0.52)

1.54

(0.66)

1.38

(0.51)

Total

2.28

(0.75)

1.78

(0.81)

1.50

(0.62)

1.44

(0.62)

1.50

(0.62)

1.50

(0.51)

1.50

(0.62)

1.39

(0.50)

CGAS

Combination

79.20

(2.39)

83.00

(2.74)

81.00

(5.47)

82.00

(5.70)

79.00

(2.24)

80.00

(6.12)

83.00

(4.47)

84.00

(2.24)

Monotherapy

73.54

(8.23)

78.84

(7.68)

79.23

(7.86)

80.38

(7.21)

82.38

(8.30)

83.46

(3.15)

82.69

(6.33)

82.38

(3.84)

Total

75.11

(7.48)

80.00

(6.85)

79.72

(7.16)

80.83

(6.69)

81.44

(7.22)

82.50

(4.28)

82.77

(5.74)

82.83

(3.48)

MADRS

Combination

9.40

(6.15)

4.40

(2.88)

4.20

(4.08)

4.80

(4.76)

6.60

(3.91)

5.60

(2.88)

3.00

(3.00)

2.80

(2.28)

Monotherapy

9.15

(6.01)

5.54

(6.03)

3.85

(4.27)

4.54

(3.62)

3.15

(3.55)

3.92

(3.01)

3.46

(3.30)

4.15

(3.84)

Total

9.22

(5.86)

5.22

(5.28)

3.94

(4.10)

4.61

(3.82)

4.11

(3.87)

4.39

(2.99)

3.33

(3.14)

3.78

(3.47)

YMRS

Combination

0.60

(1.34)

0.20

(0.45)

2.20

(3.35)

1.40

(1.67)

2.40

(3.78)

0.40

(0.55)

0.40

(0.89)

0.80

(0.84)

Monotherapy

1.92

(3.04)

1.08

(1.04)

0.77

(1.69)

1.31

(2.06)

0.85

(1.57)

1.31

(1.84)

1.00

(2.24)

1.54

(2.11)

Total

1.56

(2.71)

0.83

(0.98)

1.17

(2.25)

1.33

(1.91)

1.28

(2.37)

1.06

(1.62)

0.83

(1.94)

1.33

(1.84)

  1. CGI-S – Clinical Global Impression Severity
  2. CGAS – Clinical Global Assessment Scale
  3. MADRS – Montgomery Asperg Depression Rating Scale
  4. YMRS – Young Mania Rating Scale