Table 2 Severity of the illness at baseline and at 24 months.
Pure Mania | Mixed episode | |||
|---|---|---|---|---|
Baseline n = 504 | 24 months n = 364 (72%) | Baseline n = 262 | 24 months n = 164 (63%) | |
Consultation (n,%): | ||||
Out-patient | 352 (70%) | 354 (97%) | 169 (65%) | 156 (95%) |
In-patient | 152 (30%) | 9 (2%) | 92 (35%) | 7 (4%) |
Suicide attempt: | ||||
0 | 461 (91%)* | 317 (87%)* | 207 (79%)* | 121 (74%)* |
1 | 22 (4%)* | 32 (9%)* | 26 (10%)* | 29 (18%)* |
>1 | 10 (2%)* | 15 (4%)* | 23 (9%)* | 14 (9%)* |
Substance abuse and dependence (n,%): | ||||
Alcohol | 128 (25%) | 9 (2%) | 70 (27%) | 7 (4%) |
Cannabis | 72 (14%) | 8 (2%) | 28 (11%) | 3 (2%) |
Other substances | 29 (6%) | 2 (< 1%) | 25 (10%) | 0 (0%) |
Assessment scales: | ||||
YMRS (mean score ± SD) | 27.4 ± 8.8* | . (a) | 25.3 ± 9.0* | . (a) |
CGI (mean score ± SD): | ||||
CGI-BP Overall | 4.5 ± 1.2 | 2.4 ± 1.6 | 4.7 ± 0.8 | 2.5 ± 1.4 |
CGI-BP Mania | 4.8 ± 0.9* | 1.9 ± 1.5 | 4.6 ± 0.8* | 2.0 ± 1.3 |
CGI-BP Depression | 1.4 ± 0.5* | 1.5 ± 0.9* | 3.9 ± 0.9* | 2.1 ± 1.2* |
CGI-BP Hallucinations | 2.7 ± 1.7 | 1.4 ± 0.9* | 2.5 ± 1.6 | 1.6 ± 1.1* |
Frequency of social activities (n,%): | ||||
Never | 112 (22%)* | 44 (12%) | 77 (29%)* | 19 (12%) |
1 – 4 times | 219 (43%)* | 150 (41%) | 116 (44%)* | 91 (55%) |
≥ 5 times | 171 (34%)* | 169 (46%) | 69 (26%)* | 53 (32%) |
Impairment of work activities (n,%): | ||||
None | 70 (14%)* | 175 (48%)* | 18 (7%)* | 51 (31%)* |
Some impairment | 406 (81%)* | 166 (46%)* | 233 (89%)* | 106 (65%)* |
Satisfaction with life (n,%): | ||||
Satisfied | 160 (32%)* | 276 (76%)* | 47 (18%)* | 96 (59%)* |
Neither satisfied nor dissatisfied | 138 (27%)* | 68 (19%)* | 47 (18%)* | 37 (23%)* |
Dissatisfied | 204 (40%)* | 20 (5%)* | 166 (63%)* | 30 (18%)* |