Table 3 Prescription of antipsychotic drugs at admission and discharge, p-values of differences and chlorpromazine equivalent doses at discharge (n = 486).
FGA | ||||
|---|---|---|---|---|
Antipsychotic drug | Admission N(%) | Discharge N(%) | Adjusted P-value for the difference* | Chlorpromazine equivalent dose at discharge mean (SD) range |
Low-potency | ||||
Levomepromazine (Nozinan®) | 31(6.4) | 39(8.2) | 0.248 | 87 (99) 10–400 |
Chlorpromazine (Largactil®) | 29(6.0) | 28(5.8) | 0.793 | 171 (104) 4–400 |
Klorprotixene (Truxal ®) | 13(2.7) | 18(3.7) | 0.501 | 250 (145) 111–667 |
Thioridazine (Melleril®) | 1(0.2) | 1(0.2) | 75 | |
Medium potency | ||||
Perphenazine (Trilafon®) | 24(4.9) | 17(3.5) | 0.248 | 187 (121) 50–400 |
Perphenazine decanoate (Trilafon depot®) | 37(7.6) | 49(10.1) | 0.049 | 488 (243) 203–1624 |
Perphenazine total number patients | 60(12.4) | 65(13.4) | 0.537 | |
Zuclopentixol (Cisordinol®) | 15(3.1) | 21(4.3) | 0.501 | 58 (27) 28–128 |
Zuclopenthixol decanoate (Cisordinol Depot®) | 39(8.0) | 49(10.1) | 0.247 | 115 (61) 34–357 |
Zuclopenthixol total number patients | 51(10.5) | 68(14.0) | 0.049 | |
Dixyrazine (Esucos®) | 4(0.8) | 6(1.2) | 0.536 | 300 (300-300) |
Prochlorperazine (Stemetil®) | 1(0.2) | 1(0.2) | 1000 | |
High-potency | ||||
Haloperidol (Haldol®) | 8(1.7) | 10(2.0) | 0.613 | 144 (85) 33–267 |
Haloperidol decanoate (Haldol depot®) | 6(1.2) | 7(1.4) | 0.524 | 400 (164) 179–714 |
Haloperidol total number patients | 14(2.9) | 15(3.1) | 0.793 | |
Flupenthixol (Fluanxol®) | 2(0.4) | 3(0.6) | 0.537 | 266 (85) 33–267 |
Flupenthixol decanoate (Fluanxol depot®) | 5(1.0) | 6(1.2) | 0.793 | 247 (129) 153–429 |
Flupentixol total number patients | 7(1.4) | 9(1.9) | 0.613 | |
SGA | ||||
Olanzapine (Zyprexa®) | 122 (25.1) | 141 (29.0) | 0.049 | 350 (137) 100–800 |
Risperidone (Risperdal®) | 39(8.0) | 43(8.9) | 0.613 | 234 (107) 67–467 |
Risperidone long-acting injection (Risperdal Consta®) | 57(11.7) | 62(12.8) | 0.565 | 311 (94) 179–536 |
Risperidon total number patients | 91 (18.7) | 93 (19.1) | 0.793 | |
Quetiapine (Seroquel®) | 42(8.6) | 46(9.5) | 0.613 | 690 (533) 33–2800 |
Clozapine (Leponex®, Clozapine®) | 37(7.6) | 39(8.0) | 0.524 | |
Aripiprazole (Abilify®) | 29(6.0) | 30(6.2) | 0.793 | 285 (94) 133–400 |
Ziprazidone (Zeldox®) | 23(4.7) | 24(4.9) | 0.793 | 173 (90) 33–266 |
Amisulpride (Solian®) | 11(2.3) | 14(2.9) | 0.537 | 600 (353) 100–1200 |
Sertindole (Serdolect®) | 0(0) | 1(0.2) | missing | |
Total dose | 450 (347) 25–2800 |