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Table 1 Genotype and allele frequencies of SNPs in each gene in the Screening Sample Set (100 cases and 100 controls)

From: Association study of polymorphisms in the neutral amino acid transporter genes SLC1A4, SLC1A5 and the glycine transporter genes SLC6A5, SLC6A9with schizophrenia

Genes

Polymorphism

Genotype count

P*

Allele frequency (%)

P**

SLC1A4

SNP1

A/A

A/G

G/G

 

A

G

 
 

Schizophrenics

71

25

4

0.296

83.5

16.5

0.251

 

Controls

61

35

4

 

78.5

21.5

 
 

SNP2

C/C

C/G

G/G

 

C

G

 
 

Schizophrenics

12

35

53

0.090

29.5

70.5

0.021

 

Controls

6

27

67

 

19.5

80.5

 
 

SNP3

A/A

A/G

G/G

 

A

G

 
 

Schizophrenics

53

35

12

0.117

70.5

29.5

0.029

 

Controls

67

26

7

 

80

20

 
 

SNP4

A/A

A/G

G/G

 

A

G

 
 

Schizophrenics

25

45

30

0.315

47.5

52.5

0.547

 

Controls

17

54

29

 

44

56

 
 

SNP5

C/C

C/T

T/T

 

C

T

 
 

Schizophrenics

64

33

3

0.778

80.5

19.5

0.605

 

Controls

68

30

2

 

83

17

 
 

SNP6

A/A

A/G

G/G

 

A

G

 
 

Schizophrenics

1

22

77

0.096

12

88

0.123

 

Controls

7

22

71

 

18

82

 
 

SNP7

C/C

C/T

T/T

 

C

T

 
 

Schizophrenics

23

42

35

0.194

44

56

0.316

 

Controls

23

53

24

 

49.5

50.5

 

SLC1A5

SNP1

A/A

A/G

G/G

 

A

G

 
 

Schizophrenics

63

26

11

0.172

76.0

24.0

0.813

 

Controls

60

35

5

 

77.5

22.5

 
 

SNP2

C/C

C/G

G/G

 

C

G

 
 

Schizophrenics

36

45

19

0.964

58.5

41.5

0.839

 

Controls

37

46

17

 

60.0

40.0

 
 

SNP3

C/C

C/T

T/T

 

C

T

 
 

Schizophrenics

11

34

55

0.816

28.0

72.0

> 0.999

 

Controls

9

37

54

 

27.5

72.5

 
 

SNP4

C/C

C/T

T/T

 

C

T

 
 

Schizophrenics

51

40

9

0.819

71.0

29.0

> 0.999

 

Controls

52

37

11

 

70.5

29.5

 
 

SNP5

C/C

C/T

T/T

 

C

T

 
 

Schizophrenics

51

41

8

0.775

71.5

28.5

1.000

 

Controls

53

37

10

 

71.5

28.5

 

SLC6A5

SNP1

A/A

A/G

G/G

 

A

G

 
 

Schizophrenics

17

65

18

0.009

49.5

50.5

0.109

 

Controls

35

46

19

 

58.0

42.0

 
 

SNP2

C/C

C/T

T/T

 

C

T

 
 

Schizophrenics

20

64

16

0.022

52.0

48.0

0.107

 

Controls

37

47

16

 

60.5

39.5

 
 

SNP3

C/C

C/T

T/T

 

C

T

 
 

Schizophrenics

50

40

10

0.757

70.0

30.0

0.666

 

Controls

45

45

10

 

67.5

32.5

 
 

SNP4

A/A

A/G

G/G

 

A

G

 
 

Schizophrenics

6

40

54

0.332

26.0

74.0

0.375

 

Controls

12

37

51

 

30.5

69.5

 
 

SNP5

C/C

C/G

G/G

 

C

G

 
 

Schizophrenics

39

48

13

0.882

63.0

37.0

> 0.999

 

Controls

40

45

15

 

62.5

37.5

 
 

SNP6

C/C

C/G

G/G

 

C

G

 
 

Schizophrenics

10

43

47

0.783

31.5

68.5

0.595

 

Controls

13

43

44

 

34.5

65.5

 

SLC6A9

SNP1

C/C

C/T

T/T

 

C

T

 
 

Schizophrenics

32

48

20

0.987

56.0

44.0

> 0.999

 

Controls

31

49

20

 

55.5

44.5

 
 

SNP2

A/A

A/G

G/G

 

A

G

 
 

Schizophrenics

7

32

61

0.988

23.0

77.0

> 0.999

 

Controls

7

31

62

 

22.5

77.5

 
 

SNP3

A/A

A/G

G/G

 

A

G

 
 

Schizophrenics

6

31

63

0.830

21.5

78.5

0.720

 

Controls

6

35

59

 

23.5

76.5

 
  1. *Fisher's exact probability tests, case vs. control (2 × 3).
  2. **Fisher's exact probability tests, case vs. control (2 × 2).