Table 2 Distribution of HADS-score related to genotype of COMT in men and women.
Met/Met | Val/Met | Val/Val | ||||
|---|---|---|---|---|---|---|
No. | % | No. | % | No. | % | |
Genotypes | ||||||
Men | ||||||
Controls (HADS-D< 8 + HADS-A < 8) | 579 | 33.9 | 829 | 48.5 | 301 | 17.6 |
HADS-D ≥ 8 | 71 | 30.2 | 122 | 51.9 | 42 | 17.9 |
HADS-D ≥ 111 | 13 | 18.3 | 40 | 56.3 | 18 | 25.4 |
HADS-A ≥ 8 | 70 | 29.7 | 123 | 52.1 | 43 | 18.2 |
HADS-A ≥ 11 | 16 | 25.0 | 39 | 60.9 | 9 | 14.1 |
Combined (HADS-D ≥ 8+HADS-A ≥ 8) | 30 | 30.9 | 53 | 54.6 | 14 | 14.4 |
Unclassified (incomplete data) | 29 | 29.5 | 226 | 51.6 | 83 | 18.9 |
Women | ||||||
Controls (HADS-D< 8 + HADS-A < 8) | 549 | 30.6 | 889 | 49.5 | 358 | 19.9 |
HADS-D ≥ 8 | 96 | 35.2 | 132 | 48.4 | 45 | 16.5 |
HADS-D ≥ 111 | 27 | 32.9 | 37 | 45.1 | 18 | 22.0 |
HADS-A ≥ 8 | 125 | 34.2 | 175 | 47.8 | 66 | 18.0 |
HADS-A ≥ 11 | 46 | 37.4 | 53 | 43.1 | 24 | 19.5 |
Combined (HADS-D ≥ 8+HADS-A ≥ 8) | 47 | 37.3 | 55 | 43.7 | 24 | 19.0 |
Unclassified (incomplete data) | 227 | 32.4 | 338 | 48.2 | 136 | 19.4 |
Alleles | Met | Val | ||||
Men | ||||||
Controls | 1987 | 58.1 | 1431 | 41.9 | ||
HADS-D ≥ 8 | 264 | 56.2 | 206 | 43.8 | ||
HADS-D ≥ 112 | 66 | 46.5 | 76 | 53.5 | ||
HADS-A ≥ 8 | 263 | 55.7 | 209 | 44.3 | ||
HADS-A ≥ 11 | 71 | 55.5 | 57 | 44.5 | ||
Combined (HADS-D ≥ 8+HADS-A ≥ 8) | 113 | 58.2 | 81 | 41.8 | ||
Unclassified (incomplete data) | 484 | 55.3 | 392 | 44.7 | ||
Women | ||||||
Controls | 1987 | 55.3 | 1605 | 44.7 | ||
HADS-D ≥ 8 | 324 | 59.3 | 222 | 40.7 | ||
HADS-D ≥ 112 | 91 | 55.5 | 73 | 44.5 | ||
HADS-A ≥ 8 | 425 | 58.1 | 307 | 41.9 | ||
HADS-A ≥ 11 | 145 | 58.9 | 101 | 41.1 | ||
Combined (HADS-D ≥ 8+HADS-A ≥ 8) | 49 | 59.1 | 103 | 40.9 | ||
Unclassified (incomplete data) | 792 | 56.5 | 610 | 43.5 | ||