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Table 1 Mean cognitive test scores at baseline (week 0) and after 12, 26, 52 and 78 weeks of cholinesterase inhibitor treatment for all patients and the sub-sample who had NARTIQ scores.

From: Estimated pre-morbid IQ effects on cognitive and functional outcomes in Alzheimer disease: a longitudinal study in a treated cohort

Test (week) N All patients Mean score Standard deviation N Patients with NARTIQ scores Mean score Standard deviation
MMSE(0) 626 19.3 5.8 346 20.7 4.9
HVLT(0) 601 9.2 4.9 342 10.0 5.0
VF-Cat(0) 604 7.8 4.3 344 8.7 4.4
VF-Lex(0) 604 22.0 13.1 342 24.8 13.5
PAL(0) 461 4.3 1.8 298 4.5 1.8
DMTS(0) 447 11.1 3.1 290 11.5 2.8
MMSE(12) 143 19.5 5.5 101 20.3 5.2
HVLT(12) 84 9.7 5.6 67 10.2 5.7
VF-Cat(12) 82 8.5 5.0 66 9.0 5.3
VF-Lex(12) 82 24.3 14.9 66 25.7 15.2
PAL(12) 70 4.2 1.7 59 4.1 1.7
DMTS(12) 71 10.8 2.9 58 11.0 2.9
MMSE(26) 259 19.0 5.6 162 19.7 5.5
HVLT(26) 250 9.5 4.6 157 9.9 4.9
VF-Cat(26) 248 7.6 4.2 158 8.1 4.5
VF-Lex(26) 248 23.2 12.5 158 24.8 12.5
PAL(26) 170 4.5 1.8 124 4.4 1.7
DMTS(26) 183 11.1 3.1 127 11.2 3.0
MMSE(52) 96 18.6 5.4 75 19.0 5.3
HVLT(52) 87 9.2 5.7 69 9.3 5.8
VF-Cat(52) 87 6.9 4.5 68 7.0 4.7
VF-Lex(52) 87 23.5 13.9 68 25.0 14.0
PAL(52) 76 4.4 1.6 62 4.3 1.6
DMTS(52) 75 10.9 2.8 58 10.7 2.8
MMSE(78) 43 19.2 5.5 33 19.6 5.7
HVLT(78) 38 9.9 6.2 20 10.3 6.3
VF-Cat(78) 39 7.6 4.7 31 7.9 5.0
VF-Lex(78) 39 25.1 13.6 31 26.9 13.5
PAL(78) 29 4.3 1.8 23 4.3 1.8
DMTS(78) 33 10.6 3.4 25 10.7 3.4
  1. MMSE – Mini-Mental State Examination; HVLT – Hopkins Verbal Learning Test total score over six trials; V-Cat – Categorical Verbal Fluency; V-Lex – Lexical Verbal Fluency; PAL – Paired Associates Learning from CANTAB battery; DMTS – Delayed Matching to Sample stages from the CANTAB battery.