Table 1 Subject characteristics
| Â | Methadone substituted opiate addicts | Control subjects | ||||
|---|---|---|---|---|---|---|
| Â | whole group | without concomitant non-opioid drug use | with concomitant non-opioid drug use | whole group | without nicotine use | with nicotine use |
N | 47 | 17 | 30 | 65 | 35 | 30 |
Age | 29.3 (5.6) | 28.9 (6.6) | 29.6 (5.0) | 29.4 (6.1) | 29.3 (6.3) | 29.6 (5.8) |
Gender (m/f) | 34/13 | 11/6 | 23/7 | 45/20 | 25/10 | 20/10 |
Education | Â | Â | Â | Â | Â | Â |
+ high school | 6 | 3 | 3 | 12 | 10 | 2 |
- high school | 41 | 14 | 27 | 53 | 25 | 28 |
Clinical characteristics: | Â | Â | Â | Â | Â | Â |
Duration opiate dep. (y) | 9.5 (5.8) | 9.3 (7.6) | 9.5 (4.8) | Â | Â | Â |
Methadone substitution (month) | 19.2 (17.2) | 20.6 (19.7) | 18.4 (15.9) | Â | Â | Â |
D-L methadone (mg) | 92.0 (53.3) | 125 (58) | 73 (40) | Â | Â | Â |
D-L methadone weight ratio (mg/kg) | 1.3 (0.8) | 1.8 (0.7) | 1.1 (0.7) | Â | Â | Â |