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Table 1 Clones with differential expression patterns across all patient subgroups

From: Inflammation-related genes up-regulated in schizophrenia brains

   Fold Change    
Clone Symbol NTD (n = 11) Typical (n = 19) Atypical (n = 7) Penalized F-ratio p-value Location
1592837 IFITM2* 2.7 1.5 2.1 11.3 0.024 11p15.5
809910 IFITM3* 4.3 1.6 1.8 10.1 0.032 11p15.5
450533 SERPINA3* 4.5 1.2 7.8 8.4 0.056 14q32.1
1455976 IFITM2* 2.3 1.4 2.3 7.0 0.061 11p15.5
166245 GRIN1 -1.6 -1.3 -1.4 4.7 0.004 9q34.3
362926 PRKACB 1.4 1.7 1.5 4.6 0.012 1p36.1
323371 APP -2.9 -1.8 -1.7 4.2 0.083 21q21.2
841008 GBP1* 2.0 1.7 -1.0 4.1 0.079 1p22.2
221828 KIF1A -1.3 -1.5 -1.5 4.0 0.005 2q37.3
853906 HLA-A* 1.1 1.5 1.6 3.8 0.045 6p21.3
363007 AGXT2L1 -1.2 -1.3 -2.5 3.7 0.073 4q25
756556 SERPING1 1.3 1.2 1.4 3.6 0.048 11q12-q13.1
214162 MT1H 1.5 1.5 1.1 3.5 0.056 16q13
41447 AGTRL1 1.3 1.2 1.3 3.2 0.025 11q12
45544 TAGLN2 1.3 1.4 1.1 3.1 0.082 1q21-q25
44310 ELL -1.9 1.3 -3.1 2.9 0.153 19p13.1
487777 RB1 1.1 1.3 1.4 2.8 0.063 13q14.2
245774 C10orf10 1.4 -1.1 2.2 2.8 0.136 10q11.21
173145 CLIPR-59 -2.1 -1.1 -1.2 2.8 0.091 19q13.12
703479 HDHD1A 1.2 1.3 1.3 2.7 0.010 Xp22.32
244147 In multiple UG-clusters 1.3 2.2 1.2 2.7 0.095  
839374 EXTL2 -1.6 -1.3 -1.1 2.7 0.032 1p21
1908973 CART 1.1 1.3 1.4 2.6 0.052 5q13.2
  1. Schizophrenic patients were subdivided according to the antipsychotic medication received at death, and pooled brain samples were hybridized onto human cDNA microarrays. Twenty-three clones with large and consistent mRNA differences in all three sub-groups are listed together with their ranking statistic and parametric p-value. Four false positives are expected by chance in the list. Genes with a biological function involved in immune response (*, GO:0006955) were overrepresented in the list (p-value < 0.01). Listed P-values correspond to the parametric test of the average effect (across the subgroups) being different from the control (n = 3).