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Table 1 Basic demographic and clinical result on co-variables and putative predictors of diagnostic stability

From: Diagnostic stability among chronic patients with functional psychoses: an epidemiological and clinical study

Putative co-variables of diagnostic stability

Value

Number

25–75% Percentiles

Alcohol or drug addiction ever present

Yes

70%

 

Clinical Global Impression Scale (CGI)

5–7

50%

 

Civil status, (i.e. ever married)

Yes

69%

 

Employment at onset

Yes

66%

 

Global Assessments of Functioning (GAF)▲▲

Score

40

(35–45)

Poor premorbid social or work adjustment

Yes

71%

 

Somatic co-morbidity (any somatic illness ever present)

Yes

43%

 

Treatment response on antipsychotics

Yes

95%

 

Putative predictors of diagnostic stability

   

Age of first admission

Year

25

(20–32)

Age of onset

Year

21

(17–30)

Duration of first admission

Days

37

(8–69)

Duration of hospitalisation first year of admission

Days

107

(50–295)

Family history of psychiatric disease

Yes

81%

 

First diagnosis ICD-10 schizophrenia

Yes

23%

 

First diagnosis ICD-10 schizophrenia spectrum disorder

Yes

53%

 

Gender

Men

63%

 

Sct. Louis Criteria for Schizophrenia▲▲▲

Yes

45%

 

Year of birth

Year

1962

(1954–1970)

Measures of hospitalisation events

   

Number of hospitalisations

(#)

14

(8–26)

Total duration of hospitalisation

Years

3,4

(1,7–6,0)

Total duration of illness

Years

17

(8–24)

Year of first admission

Year

1989

(1982–1999)

Measures of diagnostic stability

   

Numbers-of-diagnostic-shifts

(#)

3

(1–6)

Numbers-of-diagnostic-spectrum-shifts

(#)

1

(0–4)

Diagnostic-complexity (numbers-of-unique-diagnoses multiplied with numbers-of-diagnostic-shifts)

(#)

8

(2–22,5)

Spectrum-complexity (numbers-of-unique-spectrum-diagnoses multiplied with numbers-of-diagnostic-spectrum shifts)

(#)

2

(0–9)

  1. Numbers of shifts between the three spectra assessed, i.e. schizophrenia spectrum, affective disorders and all others.
  2. Diagnostic complexity was calculated as the sum of the numbers-of-unique-diagnoses multiplied with numbers-of-diagnostic-shifts ICD-8 and ICD-10, respectively.
  3. Spectrum complexity was calculated as numbers-of-unique-spectrum-diagnoses multiplied with numbers-of-diagnostic-spectrum-shifts for ICD-10 translated ICD-8 and ICD-10.
  4. Eleven of the 100 subjects in the sample were identified as having possible year of onset before 1969 (the year when the psychiatric register became electronic, no further information was available), these subjects were therefore excluded from analyses.
  5. Guy, 1976; CGI scores were collapsed into the severe forms [score 5–7] vs. the milder forms [2-4].
  6. ▲▲ Endicott et al, 1976.
  7. ▲▲▲ Feighner et al, 1972.