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Table 2 Allele and genotype frequency at marker rs 175174 in schizophrenic psychoses

From: ZDHHC8as a candidate gene for schizophrenia: Analysis of a putative functional intronic marker in case-control and family-based association studies

 

Allele (%)

 

Genotypes (%)

 

Samples

A

G

p-value

AA

AG

GG

p-value

total

       

   SCZ (N = 433)

527 (60.9)

339 (39.1)

0.48

154 (35.6)

219 (50.6)

60 (13.9)

0.43

   CON (N = 186)

235 (63.2)

137 (36.8)

 

71 (38.2)

93 (50.0)

22 (11.8)

 

females

       

   SCZ (N = 112)

125 (55.8)

99 (44.2)

0.25

30 (26.8)

65 (58.0)

17 (15.2)

0.20

   CON (N = 81)

100 (61.7)

62 (38.3)

 

27 (33.3)

46 (56.8)

8 (9.9)

 

males

       

   SCZ (N = 321)

402 (62.6)

240 (37.4)

0.68

124 (38.6)

154 (48.0)

43 (13.4)

0.66

   CON (N = 105)

135 (64.3)

75 (35.7)

 

44 (41.9)

47 (44.8)

14 (13.3)

 

family history

       

   sporadic SCZ (N = 369)

441 (59.8)

297 (40.2)

0.12

124 (33.6)

193 (52.3)

52 (14.1)

0.10

   familial SCZ (N = 64)

86 (67.2)

42 (32.8)

 

30 (46.9)

26 (40.6)

8 (12.5)

 
  1. SCZ: probands with schizophrenia; CON: controls; p-values for alleles (Fisher's exact test) and genotypes (Armitage's trend test).