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Table 1 Gender differences at baseline*

From: Acute weight gain, gender, and therapeutic response to antipsychotics in the treatment of patients with schizophrenia

 

All patients

Women

Men

 

Characteristic

N = 1996

N = 700

N = 1296

P

Demographics

    

   Age

38.6 (11.4)

40.9 (12.8)

37.3 (10.4)

<0.001

   Race

   

0.013

Caucasian

1600 (80.2%)

587 (83.9%)

1013 (78.2%)

0.002

African descent

220 (11.0%)

67 (9.6%)

153 (11.8%)

0.128

Hispanic

83 (4.2%)

19 (2.7%)

64 (4.9%)

0.018

Other

93 (4.7%)

27 (3.9%)

66 (5.1%)

0.211

   Diagnosis

   

<0.001

Schizophrenia

1658 (83.1%)

526 (75.1%)

1132 (87.3%)

<0.001

Schizoaffective disorder

300 (15.0%)

157 (22.4%)

143 (11.0%)

<0.001

Schizophreniform disorder

38 (1.9%)

17 (2.4%)

21 (1.6%)

0.207

Core schizophrenia symptoms

    

   BPRS total

33.4 (10.7)

33.5 (11.2)

33.3 (10.5)

0.660

   BPRS positive

10.3 (4.1)

10.0 (4.1)

10.5 (4.0)

0.017

   BPRS negative

6.7 (3.3)

6.7 (3.4)

6.7 (3.3)

0.791

Depressive symptoms

    

   MADRS

16.6 (8.8)

17.3 (9.3)

16.3 (8.5)

0.031

   BPRS anxiety and depression

7.5 (3.8)

8.0 (3.9)

7.3 (3.8)

<0.001

Functional status

    

   SF-36 physical component

43.6 (13.0)

41.4 (14.0)

44.5 (12.5)

0.004

   SF-36 mental component

34.6 (12.4)

34.6 (12.9)

34.6 (12.2)

0.958

Weight

    

   Weight, kg

76.8 (17.1)

70.2 (16.4)

80.4 (16.3)

<0.001

   BMI

26.0 (5.2)

26.5 (5.8)

25.8 (4.9)

0.007

   BMI level

   

<0.001

Underweight to average (BMI < 25)

930 (48.9%)

319 (47.6%)

611 (49.6%)

0.418

Overweight (BMI ≥ 25 and < 30)

609 (32.0%)

191 (28.5%)

418 (33.9%)

0.016

Obese (BMI ≥ 30)

364 (19.1%)

160 (23.9%)

204 (16.5%)

<0.001

  1. * Data are presented as Mean (SD) or N (%).
  2. P-values refer to differences between women and men.