Skip to main content

Table 2 Mean (± SD) SKAMP Total Scores at Each Observation Session for Each Treatment at Each Dose Levela

From: Efficacy of two once-daily methylphenidate formulations compared across dose levels at different times of the day: Preliminary indications from a secondary analysis of the COMACS study data

 

MCD

CON

PLA

Observation Session (hrs)

Low

Med

High

Low

Med

High

Low

Med

High

0

18.48 (11.82)

20.88 (12.95)

19.91 (13.15)

18.04 (10.13)

19.14 (12.14)

21.47 (13.06)

13.58 (9.72)

16.02 (11.84)

13.96 (11.14)

1.5

11.44 (7.99)

10.98 (8.62)

6.55 (5.85)

14.04 (9.85)

14.86 (12.01)

11.34 (9.71)

19.10 (12.83)

19.47 (12.56)

18.88 (13.48)

3.0

12.57 (9.92)

11.03 (9.66)

7.31 (6.10)

16.44 (12.43)

15.29 (12.72)

12.62 (11.00)

21.47 (14.61)

20.98 (14.11)

22.11 (14.10)

4.5

13.46 (11.53)

12.39 (10.32)

9.15 (8.62)

17.55 (13.37)

15.09 (12.60)

13.55 (11.91)

20.23 (11.92)

22.09 (15.46)

23.44 (12.55)

6.0

16.08 (13.27)

14.47 (11.53)

10.30 (9.71)

17.00 (12.12)

14.28 (11.73)

12.04 (11.62)

22.98 (12.79)

22.15 (13.91)

26.02 (14.56)

7.5

15.85 (11.21)

17.26 (13.63)

14.29 (12.55)

18.62 (12.66)

15.19 (13.47)

13.47 (12.97)

23.54 (12.96)

23.13 (14.72)

24.48 (14.68)

12.0

20.44 (13.75)

20.28 (15.02

19.85 (14.41)

16.90 (13.36)

17.81 (13.84)

16.74 (14.98)

19.45 (13.46)

20.73 (13.46)

22.02 (15.17)

  1. a Lower SKAMP scores indicate greater efficacy
  2. CON = Concerta; MCD = Metadate CD; PLA = placebo. Low = Low Dose (CON 18 mg; MCD 20 mg), Med = Medium Dose (CON 36 mg; MCD 40 mg), Hi = High Dose (CON 54 mg ; MCD 60 mg).