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Table 3 Comparison of hormone parameters:AUC for the first (23.00 h – 3.00 h) and second (3.00 h – 7.00 h) half of the night.

From: The Renin-Angiotensin-Aldosterone system in patients with depression compared to controls – a sleep endocrine study

  depressed patients AUC controls AUC significance
1. half    
ACTH (pg/ml × min) 3180 ± 1608 3193 ± 1074 n.s.
cortisol (ng/ml × min) 23690 ± 15330 11002 ± 4945 (n.s) p = 0.06
renin (pg/ml × min) 1656 ± 1000 1359 ± 249 n.s.
aldosterone (pg/ml × min) 9370 ± 5404 2914 ± 2932 p = 0.022
2. half    
ACTH (pg/ml × min) 5601 ± 1741 6807 ± 2452 n.s.
cortisol (ng/ml × min) 45682 ± 17309 33395 ± 8991 n.s.
renin (pg/ml × min) 1588 ± 919 1504 ± 433 n.s.
aldosterone (pg/ml × min) 16075 ± 5908 6799 ± 4469 p = 0.009