Skip to main content

Table 3 Treatment response - completers analyses

From: The effectiveness of integrated treatment in patients with substance use disorders co-occurring with anxiety and/or depression - a group randomized trial

Response variables

Parameter

Unadjusted

Adjusted

  

Estimate

Sig.

95% CI

Estimate

Sig.

95% CI

    

Lower bound

Upper bound

  

Lower bound

Upper bound

AUDIT

6 months

−2.20

0.141

−5.14

0.74

−2.22

0.137

−5.15

0.72

12 months

−3.53

0.017

−6.41

−0.65

−3.53

0.017

−6.41

−0.65

IG*6 m

−3.18

0.057

−6.46

0.099

−2.72

0.106

−6.02

0.59

IG*12 m

−2.76

0.097

−6.03

0.51

−2.35

0.160

−5.64

0.94

DUDIT

6 months

−0.97

0.615

−4.80

2.86

−0.98

0.612

−4.81

2.84

12 months

−4.18

0.029

−7.92

−0.43

−4.18

0.029

−7.92

−0.43

IG*6 m

1.51

0.784

−11.80

14.82

−1.45

0.806

−15.87

12.96

IG*12 m

2.49

0.652

−10.82

15.79

−0.48

0.935

−14.89

13.93

SCL-90-anxiety

6 months

−0.13

0.418

−0.45

0.19

−0.13

0.429

−0.45

0.19

12 months

−0.17

0.289

−0.49

0.15

−0.17

0.285

−0.49

0.15

IG*6 m

0.34

0.230

−0.22

0.89

0.38

0.204

−0.21

0.97

IG*12 m

0.22

0.429

−0.33

0.78

0.27

0.372

−0.33

0.86

SCL-90-depres-sion

6 months

−0.20

0.372

−0.63

0.24

−0.19

0.374

−0.63

0.24

12 months

−0.36

0.097

−0.80

0.07

−0.37

0.094

−0.80

0.06

IG*6 m

0.27

0.501

−0.66

1.19

0.34

0.393

−0.57

1.25

IG*12 m

0.18

0.646

−0.75

1.11

0.25

0.525

−0.66

1.16

SCL-90-GSI

6 months

−0.16

0.257

−0.45

0.12

−0.16

0.260

−0.45

0.12

12 months

−0.13

0.353

−0.42

0.15

−0.14

0.345

−0.42

0.15

IG*6 m

0.39

0.200

−0.30

1.09

0.43

0.157

−0.23

1.08

IG*12 m

0.15

0.595

−0.54

0.85

0.18

0.511

−0.48

0.84

ASI-alcohol

6 months

−6.28

0.001

−9.96

−2.61

−6.40

0.001

−10.09

−2.72

12 months

−4.29

0.020

−7.90

−0.69

−4.29

0.020

−7.91

−0.68

IG*6 m

−0.72

0.723

−4.70

3.27

1.86

0.432

−3.56

7.29

IG*12 m

−3.40

0.093

−7.38

0.58

−1.05

0.648

−6.44

4.34

ASI-Illegal substances

6 months

−5.41

0.182

−13.41

2.58

−5.41

0.182

−13.40

2.58

12 months

−6.24

0.125

−14.23

1.76

−6.24

0.125

−14.23

1.76

IG*6 m

10.32

0.315

−13.15

33.79

10.94

0.308

−13.90

35.78

IG*12 m

8.90

0.381

−14.56

32.37

9.55

0.368

−15.28

34.38

SATS-R

6 months

1.65

<0.001

0.81

2.49

1.65

<0.001

0.81

2.49

12 months

2.35

<0.001

1.51

3.19

2.35

<0.001

1.51

3.19

IG*6 m

1.76

0.070

−0.19

3.71

1.63

0.050

0.001

3.25

IG*12 m

2.18

0.034

0.22

4.14

2.07

0.020

0.44

3.70

  1. Examining differences between the Intervention Group and the Control Group in regard to treatment response – Completers analyses.
  2. Completers = Having received at least 5 sessions and met for at least one follow-up session.
  3. 6 months = The change of the Control group between baseline and 6 months. 12 months = The change of the Control group between baseline and 12 months. IG*6 m = The additional change of the Intervention group between baseline and 6 months compared to the Control Group. IG*12 m = The additional change of the Intervention group between baseline and 12 months compared to the Control Group. AUDIT = The Alcohol Use Disorder Identification Test, DUDIT = The Drug Use Disorder Identification Test, SCL-90-Anxiety = The Symptom Check List 90 anxiety sum score, SCL-90-Depression = The Symptom Check List 90 depression sum score, SCL-90-GSI = The Symptom Check List 90 Global Severity Index sum score, ASI-Alcohol = The European Addiction Severity Index, number of days using alcohol on a regular basis during the last 30 days, ASI-Illegal substances = The European Addiction Severity Index, number of days using any illegal substances during the last 30 days, SATS-R = The Substance Abuse Treatment Scale, revised.
  4. Statistical significant values are written in bold types, a 5% alfa-level is used.
  5. A linear multilevel model is used. The different response variables are modelled as a function of group and time. The clustering in the data is accounted for by a random intercept at patient level and at centre level. The primary target of analysis was the interaction between group and time. The analyses where adjusted for by the following covariates: Age, Gender, Being in a relationship, Having his/her own apartment, Having paid work and Having compulsory school only or senior high school. During the adjusted analyses a non-restricted Log likelihood was used. In the final models, the restricted Log Likelihood was used.